@ARTICLE{Ziółkowski_H._CD4-_2018, author={Ziółkowski, H. and Maślanka, T. and Socha, P. and Ziółkowska, N. and Dąbrowski, M. and Małaczewska, J.}, volume={vol. 21}, number={No 2}, journal={Polish Journal of Veterinary Sciences}, howpublished={online}, year={2018}, publisher={Polish Academy of Sciences Committee of Veterinary Sciences}, publisher={University of Warmia and Mazury in Olsztyn}, abstract={The aim of the present study was to investigate whether the anterior chamber constitutes part of the normal migratory pathway of CD4+ and CD8+ lymphocytes in cattle and swine. The cells obtained from aqueous humor of cows and pigs were stained for CD4 and CD8 receptors, and subsequently analyzed with flow cytometry. The mean percentage of CD4+CD8-, CD4-CD8+ and CD4+CD8+ cells within the total lymphocyte population of the bovine anterior chamber was, respectively, 17.88, 12.64 and 27.26%. In turn, the mean values of these parameters in pigs were 1.77, 38.48 and 17.45, respectively. Among bovine and porcine CD4+CD8+ cells prevalent were those displaying CD4lowCD8low and CD4lowCD8high phenotypes, respectively. The results suggest that the anterior chamber in cattle and swine is an element in the normal migratory pathway of CD4+, CD8+ and CD4+CD8+ cells. Furthermore, the contribution of these subsets in the anterior chamber lymphocyte population can differ considerably between animal species.}, type={Artykuły / Articles}, title={CD4- and CD8-expressing cells found in the bovine and porcine anterior chamber of the eye}, URL={http://journals.pan.pl/Content/106868/PDF/07.pdf}, doi={10.24425/122596}, keywords={anterior chamber, CD4+ cells, CD8+ cells, DP cells, cattle, pig}, }