TY - JOUR N2 - The prevalence of vitamin D deficiency in the American and European population is estimated to be extremely high. Although fewer people today suff er from serious health problems related to calcium and phosphate metabolism resulting from vitamin D deficiency, there are more and more studies suggesting that calcitriol may play an important role in the pathogenesis of other diseases in virtually every body system. A growing body of research shows that through its ubiquitously expressed receptor, calcitriol displays potent anti-angiogenic an anti-inflammatory activity. Th is review summarizes recent discoveries regarding these non-classical eff ects of vitamin D and their clinical implications. Data collection focused on the prevention and treatment of ocular diseases as well as on the underlying mechanisms. L1 - http://journals.pan.pl/Content/108797/PDF/FMC%202-18%209-Skowron.pdf L2 - http://journals.pan.pl/Content/108797 PY - 2018 IS - No 2 EP - 118 DO - 10.24425/fmc.2018.124662 KW - vitamin D KW - dihydroxycholecalciferol KW - calcitriol KW - vitamin D receptor KW - ophthalmology KW - angiogenesis KW - inflammation KW - retinopathy KW - retinoblastoma KW - age-related macular degeneration KW - corneal epithelium A1 - Skowron, Kamil A1 - Pawlicka, Ilona A1 - Gil, Krzysztof PB - Oddział PAN w Krakowie; Uniwersytet Jagielloński – Collegium Medicum VL - vol. 58 DA - 2018.06.30 T1 - The role of vitamin D in the pathogenesis of ocular diseases SP - 103 UR - http://journals.pan.pl/dlibra/publication/edition/108797 T2 - Folia Medica Cracoviensia ER -