TY - JOUR N2 - We described a first case of resistance to eprinomectin in goat herd in Poland in which resistance to benzimidazoles had been previously reported. The herd was established in 2011 by purchasing several goats from a single herd in south-eastern Poland. Resistance to benzimidazoles in the herd was first reported in 2017. Shortly after the owner started to signal low effectiveness of the treatment with eprinomectin. In June 2018 the larval development test from pooled faecal sample was performed and the results indicated the presence of resistance to macrocyclic lactones and levamisole. In July 2018 a faecal egg count (FEC) reduction test was performed in 39 animals with levamisole, eprinomectin and one untreated control group. Drugs were used in doses recommended for goats. Three methods of calculation of FEC reduction were compared. After eprinomectin treatment, FEC reduction ranged from 0 to 20%, depending on the method of calculation. FEC reduction following levamisole treatment was 100%. Main species present in the faecal samples after treatment and in larvicidal concentrations in larval development test was Haemonchus contortus. This is the first report of anthelminthic resistance to macrocylic lactones (eprinomectin) in goats in Poland. L1 - http://journals.pan.pl/Content/114785/PDF/15.pdf L2 - http://journals.pan.pl/Content/114785 PY - 2019 IS - No 4 EP - 760 DO - 10.24425/pjvs.2019.131404 KW - anthelmintic resistance KW - eprinomectin KW - levamisole KW - faecal egg count reduction test KW - larval development test KW - Haemonchus contortus KW - Trichostrongylus spp. KW - Teladorsagia spp. KW - goats A1 - Mickiewicz, M. A1 - Czopowicz, M. A1 - Moroz, A. A1 - Szaluś-Jordanow, O. A1 - Górski, P. A1 - Várady, M. A1 - Königová, A. A1 - Spinu, M. A1 - Lefkaditis, M. A1 - Kaba, J. PB - Polish Academy of Sciences Committee of Veterinary Sciences PB - University of Warmia and Mazury in Olsztyn VL - vol.22 DA - 2019.12.27 T1 - Development of resistance to eprinomectin in gastrointestinal nematodes in a goat herd with pre-existing resistance to benzimidazoles SP - 753 UR - http://journals.pan.pl/dlibra/publication/edition/114785 T2 - Polish Journal of Veterinary Sciences ER -