Ghrelin and its correlation with leptin, energy related metabolites and thyroidal hormones in dairy cows in transitional period

Journal title

Polish Journal of Veterinary Sciences




No 1

Publication authors

Divisions of PAS

Nauki Biologiczne i Rolnicze


Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn




ISSN 1505-1773


McGowan (1983), A peroxidase - coupled method for the colorimetric determination of serum triglycerides, Clin Chem, 29, 538. ; Schwartz (2000), Central nervous system control of food intake, Nature, 661. ; Itoh (2005), GH secretory responses to ghrelin and GHRH in growing and lactating dairy cattle, Domest Anim Endocrinol, 28, 34, ; Chilliard (2005), Leptin expression in ruminants : nutritional and physiological regulations in relation with energy metabolism, Domest Anim Endocrinol, 29, 3, ; Romo (1997), Dietary fatty acids modulate hormone responses in lactating cows : mechanistic role for ` - deiodinase activity in tissue, Domest Anim Endocrinol, 14, 409, ; Oetzel (2004), Monitoring and testing dairy herds for metabolic disease, Vet Clin North Am Food Anim Pract, 20, 651, ; Block (2001), Decreased concentration of plasma leptin in periparturient dairy cows is caused by negative energy balance, J Endocrinol, 171, 339, ; Ingvartsen (2000), Integration of metabolism and intake regulation : a review focusing on periparturient animals, J Dairy Sci, 83, 1573, ; Huszenicza (2002), Clinical endocrinology of thyroid gland function in ruminants, Vet Med Czech, 47, 199. ; De Vriese (2008), Ghrelin : a new peptide regulating growth hormone release and food intake, Int J Biochem Cell Biol, 40, 1420, ; Grohn (1983), Fatty infiltration of liver in spontaneously ketotic dairy cows, J Dairy Sci, 66, 2320, ; Bell (1995), Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation, J Anim Sci, 73, 2804. ; Drackley (2001), Adaptations of glucose and long - chain fatty acid metabolism in liver of dairy cows during the periparturient period, J Dairy Sci, 100, ; Drackley (1999), ADSA Foundation Scholar Award Biology of dairy cows during the transition period : the final frontier, J Dairy Sci, 82, 2259, ; Herdt (2000), Variability characteristics and test selection in herd - level nutritional and metabolic profile testing, Vet Clin North Am Food Anim Pract, 16, 387, ; Reist (2002), Estimation of energy balance at the individual and herd level using blood and milk traits in high - yielding dairy cows, J Dairy Sci, 85, 3314, ; Mohlig (2002), Euglycemic hyperinsulinemia , but not lipid infusion , decreases circulating hrelin levels in humans, J Endocrinol Invest, 25, 36, ; Sevinc (2003), Lipid and lipoprotein levels in dairy cows with fatty liver, Turk J Vet Anim Sci, 27, 295. ; Asl (2011), Prevalence of subclinical ketosis in dairy cattle in the Southwestern Iran and detection of cutoff point for NEFA and glucose concentrations for diagnosis of subclinical ketosis, Prev Vet Med, 100, 38, ; Soares (2008), Ghrelin des - acyl ghrelin and obestatin : three pieces of the same puzzle, Peptides, 29, 1255, ; Holtenius (1989), Plasma lipids in normal cows around partus and in cows with metabolic disorders with and without fatty liver, Acta Vet Scand, 30, 441. ; Bauman (2000), Regulation of nutrient partitioning during lactation : homeostasis and homeorhesis revisited In ed Ruminant Metabolism Growth and Reproduction CABI Publishing , New York pp, Physiology Digestion, 311. ; Kurose (2005), Changes in expression of the genes for the leptin receptor and the growth hormone - releasing peptide / ghrelin receptor in the hypothalamic arcuate nucleus with long - term manipulation of adiposity by dietary means, J Neuroendocrinol, 17, 331, ; Kasagić (2011), Endocrine and metabolic profile in Holstein and red Holstein heifers during peripartal period, Acta Vet Beograd, 61, 555, ; Djokovic (2007), Blood concentrations of thyroid hormones and lipids and content of lipids in the liver in dairy cows in transitional period, Acta Vet Brno, 525, ; Melendez (2002), Metabolic responses of transition Holstein cows fed anionic salts and supplemented at calving with calcium and energy, J Dairy Sci, 85, 1085, ; Bertoni (2009), Some new aspects of nutrition , health conditions and fertility of intensively reared dairy cows, Ital J Anim Sci, 8, 491, ; Bradford (2008), Negative energy balance increases periprandial ghrelin and growth hormone concentrations in lactating dairy cows, Domest Anim Endocrinol, 34, 196, ; Nikolić (1997), Low peripheral serum thyroid hormone status independently affects the hormone profile of healthy and ketotic cows during the first week pos - partum, Acta Vet Beograd, 47, 3. ; Gentry (2003), Ghrelin a growth hormone secretagogue , is expressed by bovine rumen, J Dairy Sci, 1. ; Etherton (1998), Biology of somatotropin in growth and lactation of domestic animals, Physiol Rev, 78, 745. ; Briatore (2003), Acute plasma glucose increase , but not early insulin response , regulates plasma ghrelin, Eur J Endocrinol, 149, 403, ; Goff (1997), Physiological changes at parturition and their relationship to metabolic disorders, J Dairy Sci, 1260, ; Djoković (2014), Endocrine and Metabolic Status of Dairy Cows during Transition Period, Thai J Vet Med, 44, 59. ; Hayashida (2001), Ghrelin in domestic animals : distribution in the stomach and its possible role, Domest Anim Endocrinol, 21, 17, ; Wertz (2006), Circulating ghrelin concentrations fluctuate relative to nutritional status and influence feeding behavior in cattle, J Anim Sci, 84, 3285, ; Yamada (2003), The relationship between plasma leptin concentrations and distribution of body fat in crossbred steers, Anim Sci J, 74, 95, ; Pezzi (2003), - deiodinase activity and circulating thyronines in lactating cows, J Dairy Sci, 86, 152, ; Hegardt (1999), Mitochondrial - hydroxy - - methylglutaryl - CoA synthase : a control enzyme in ketogenesis, Biochem J, 569, ; Ehrhardt (2000), Development of a specific radioimmunoassay to measure physiological changes of circulating leptin in cattle and sheep, J Endocrinol, 166, 519, ; Carulli (1999), Regulation of ob gene expression : evidence for epinephrine - induced suppression in human obesity, J Clin Endocrinol Metab, 84, 3309, ; Veenhuizen (1991), Metabolic changes in blood and liver during development and early treatment of experimental fatty liver and ketosis in cows, J Dairy Sci, 74, 4238, ; Duffield (1998), Efficacy of monensin for the prevention of subclinical ketosis in lactating dairy cows, J Dairy Sci, 81, 2866, ; Ahima (2000), Leptin, Annu Rev Physiol, 62, 413,