Details

Title

Serum malondialdehyde level and activity of total antioxidant status of dogs with age-related cataract

Journal title

Polish Journal of Veterinary Sciences

Yearbook

2016

Numer

No 2

Publication authors

Divisions of PAS

Nauki Biologiczne i Rolnicze

Abstract

<jats:title>Abstract</jats:title><jats:p>Study objective: determination of malondialdehyde (MDA) level and total antioxidant status (TAS) in the serum of dogs with age-related cataract.</jats:p><jats:p>Material and methods: Forty dogs, 10-16 years of age, which were diagnosed with age-related cataract were examined. The control group consisted of 12 dogs, 8-13 years of age, without cataract. MDA was determined using a Perkin-Elmer LS 30 luminescence spectrometer using the method with thiobarbituric acid (TBA). TAS was determined using the colorimetric method with a set of Randox Total Antioxidant Status reagents.</jats:p><jats:p>Results: The results show a higher level of MDA with statistically significant difference and lower activity of TAS in the serum of dogs with age-related cataract.</jats:p><jats:p>Conclusions: The results obtained indicate higher systemic lipid peroxidation and weakening of the general defense system in dogs with age-related cataract. These results suggest that such conditions may have an effect on the development of age-related cataract and are consistent with the theory of free radical age-related cataract development.</jats:p>

Publisher

Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn

Date

2016

Identifier

ISSN 1505-1773

DOI

10.1515/pjvs-2016-0054

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