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Number of results: 18
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Abstract

Introduction: Acute subdural hematoma (aSDH) removal is one of the most commonly performed procedure in neurosurgery. Complications of those surgeries which require reoperation are associated with higher risk of poor treatment outcome. Th erefore we decided to analyse potential factors which might be associated with risk of early reoperation among patients who underwent aSDH surgery. Material and methods: We retrospectively analysed 328 patients treated due to aSDH. From their medical records we obtained detailed medical history. Early reoperation was defi ned as reoperation during the same hospital stay. To determine the potential predictors of early reoperation we used univariate and multivariate logistic regression analyses. Results: A total of 20 (6.09%) patients required early reoperation. Th ose patients had signifi cantly higher International Normalized Ratio (INR) upon admission (1.96 ± 2.55 vs. 1.26 ± 0.50; p <0.01) and signifi cantly higher Prothrombin Time (PT) upon admission (21.84 ± 27.10 vs. 13.40 ± 3.45; p <0.01). In multivariate logistic regression analysis aft er adjustment for all possible confounders higher INR (OR: 1.762; 95% CI: 1.017–22.840; p = 0.045) remained independently associated with higher risk of early reoperation among patients with aSDH. Conclusions: Patients with higher INR and PT upon admission are at higher risk of early reoperation. Higher INR is independently associated with higher risk of early reoperation among patients with aSDH.
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Abstract

Both sarcoidosis and primary Sjögren syndrome (pSS) are multisystem disorders of unknown etiology, which share certain clinical features, making the diff erential diagnosis a real challenge in clinical practice. Several published case reports and case series have posed the question as to whether there is a real association — mimicry between the two diseases or it is just coincidence. We attempt, aft er systematic and comprehensive research of the relevant published literature, to present all those data, clinical or paraclinical, which could be useful in the diagnostic approach and the distinguishment of the two diseases. It is certain that, besides the classic diagnostic methods, emerging is the role of immunology and genetics on this direction, although not established yet.
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Abstract

Objective: The goal of this contribution is to present and familiarize the medical community with the method for the assessment of trace and essentials elements in prostate tissue sections. Materials and methods: X-ray fl uorescence based technique (namely Synchrotron Induced X-ray Emission (SRIXE)) is described in terms of methodology, sample preparation and the evaluation of the recorded results (spectral data sets). Materials for the samples were collected from the patients underwent radical prostatectomy due to Adenocarcinoma prostatae. Specimens were freeze-dried, cut by microtome (to the thickness of 15 μm), one slice was placed on Mylar foil (for SRIXE measurements) and adjacent one on microscopic glass (for histopathological assessment). Results: Results presented here show the usability of SRIXE method for the evaluation of concentration of trace and essential elements in prostate tissue sections with the spatial resolution better than 15 microns. Discussion: Histopathological analysis of samples, which is only focused on morphological features, is unable to reveal information about changes in biochemical signature of tissues aff ected by the illness. SRIXE is a powerful and promising technique to analyse even very low concentrations of selected elements at the cellular level without any labelling or separating procedures. Obtained results may be correlated with classic histopathological assessment allowing for drawing conclusions on the changes in certain elements concentrations with the progression of disease. Moreover, mentioned in this work analysis, can be performed for any type of biological tissues.
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Abstract

Background and objective: Urological diseases represent a signifi cant health issue worldwide. Presented study aimed at assessing current urological knowledge and confi dence in performing urological diagnostic and therapeutic procedures among medical students at Jagiellonian University Medical College in Poland and compare it on diff erent stages of the undergraduate medical education. Material and methods: We designed an anonymous survey distributed among Polish students from 1st to 6th year of medical studies, before and aft er clinical urology course. Questions concerned general urological knowledge, prostate diseases, erectile dysfunction, and self-reported practical urological skills. Results: Overall, 437 respondents participated in the survey. Mean total test score in our study groupwas 50.08%, mean general urological knowledge score was 53.44%, mean prostate diseases knowledge score was 55.43%, mean erectile dysfunction score was 36% and mean practical skills score was 45.83%. Mean total test score increased with consecutive years of studies (R = 0.58; p <0.001). Th e risk of an above average total test score was signifi cantly infl uenced by the urology course (OR = 7.95, 95%CI = 1.81–34.84, p = 0.006) and the year of medical studies (4th–6th vs. 1st–3rd) (OR = 5.16, 95%CI = 3.41–7.81, p <0.001). Practical skills score above average was signifi cantly more frequent in the group aft er the urology course (OR = 6.75, 95%CI = 1.54–29.58, p = 0.011). Conclusions: Results of this study reveal low mean scores obtained by students, even aft er completing the urology course, which implies that curriculum requires further development. Urological knowledge and self-assessed practical skills increased with years of medical education. The urology course improved the score obtained in our survey, both in terms of total test score and practical skills.
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Abstract

Background: Unhealthy diet and cooking method used may infl uence the risk of breast cancer (BC), but there is only limited evidence with regard to benign breast disease (BBD). The aim of this study was to assess a relationship between cooking technique, especially fried to boiled meals ratio in the diet, and the risk of BC and BBD in a group of Polish women. Material and methods: A case-control study involving 34 BC cases, 81 BBD cases and 122 healthy controls was conducted between July 2007 and November 2011. All the women were asked about their nutritional habits, especially the way of preparing meat and fi sh dishes. Th en the ratio of fried to boiled meals was calculated. Results: High fried to boiled ratio was associated with increasing risk of BBD, but not BC. Women consuming fried dishes more oft en than boiled dishes had elevated risk of BBD: OR = 3.04 and OR = 3.65 for the second and the third tertile, respectively. Adjustment for the other confounders only slightly altered this relationship. Conclusion: Women who preferred frying as a cooking technique had increased risk of benign breast disease, but not breast cancer. Th ere is a need of more precise investigation to confi rm this association.
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Abstract

Developing the empathic attitude is one of the tasks of medical education as it aff ects the quality of therapeutic contact in the relationship between the doctor and the patient, conditioning the treatment process. According to Davis’s concept, empathy is defi ned as an aff ective-cognitive reaction in the context of the other person’s experience. Aim: Analysis of profi les of empathic sensitivity in students of medicine. Group: Male and female students of the fi ft h year of medicine who agreed to participate in an anonymous study (n = 153; M = 57, F = 96; mean age: 23 years). Tools: Th e Empathetic Sensitivity Scale (EES), which is the Polish tool for Davis’s Interpersonal Reactivity Index (IRI) was used. Th e ESS includes three sub-scales: Empathic Care (EC), Personal Distress (PD) and Adopting Perspective (AP). Results: The raw results were converted into sten scores and for sten scores for all three dimensions of empathetic sensitivity no diff erences were found between male and female students. Th ree clusters (1: n = 33%, 2: n = 39%, 3: n = 28%), which diff er in terms of each distinguished indicator, were identifi ed. Conclusions: Th e first cluster characterizes empathetic people, both in the aff ective and cognitive spheres, and those dealing well with unpleasant emotions in situations diffi cult to others. Th e second cluster characterizes participants with the ability to recognize the needs of others and to take into account their perspectives; the third cluster includes participants with a tendency to focus on their own experiences emerging in response to other people’s suff ering but with the ability to understand a situation and show empathic concern for the other person. The most favourable profi le — for a future doctor as well as for his patients — is the fi rst cluster because the doctor, with his empathic sensitivity directed towards the other man, can deal with his own unpleasant emotions.
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Abstract

Th e forearm is a body region of numerous anatomical variations. Due to its favorable anatomy fl exor digitorum superfi cialis muscle (FDS) is commonly used in tendon transfer surgeries. In this study a unique combination of abnormalities was found in a single forearm: the fl exor digitorum superfi cialis muscle penetrated by the median nerve, one of the fl exor digitorum superfi cialis tendons early division and absence of the palmaris longus muscle. Described variation potentially may lead to the clinical manifestation of the median nerve compression and should be also considered during FDS surgery.
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Abstract

Background: Air pollution is a severe problem in Poland, with Kraków area being among the regions with the worse air quality. Viral croup or pseudocroup is a common childhood disease that may manifest with severe upper respiratory tract obstruction. Our aim was to evaluate the associations between incidence and severity of viral croup symptoms among children living in Kraków area, Poland, and air pollution. Methods: Th e retrospective cross-sectional study included Kraków area residents <18 years of age admitted to the Emergency Department of St. Louis Children Hospital in Kraków, Poland over 2-year period. Daily mean concentrations of air pollutants: particulate matter (PM10 and PM2.5), nitric oxides (NOx), carbon oxide (CO), sulfur dioxide, ozone, and benzene were retrieved from public database of measurements performed at three local stations. Numbers of cases of viral croup per week were correlated with weekly mean concentrations of air pollutants. Mean air temperature was treated as a cofactor. Results: During the studied period, mean concentrations of PM10, PM2.5, and NOx exceeded the allowable levels (yearly means) specifi ed by Polish law regulations. Signifi cant positive correlations of moderate strength were observed between weekly mean concentrations of most air pollutants, especially PM10, PM2.5, CO and benzene, and numbers of cases of viral croup recorded per week, confi rmed in the analysis restricted to non-holiday period and to winter months only. Th e correlations between NOx, CO, benzene and croup prevalence were independent of temperature in non-holiday period. Conclusions: Our results support adverse impact of air pollution on children’s respiratory health.
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Abstract

Introduction: Interventional cardiology (IC) is a rapidly expanding fi eld of medicine. Medical studies should provide students the necessary level of knowledge about new techniques in IC. The aim of the study was to assess the medical students’ knowledge about various new areas of IC. Material and methods: Self-designed questionnaire was used to assess student’s knowledge. It contained 31 questions. Th e initial 3 questions concerned general information, the remaining ones were related to diff erent IC techniques: Transcatheter Aortic Valve Implantation (TAVI), Bioresorbable Vascular Scaff old (BVS), percutaneous mitral regurgitation repair methods, Left Atrial Appendage Occlusion (LAAO), Renal DeNervation (RDN), Balloon Aortic Valvuloplasty (BAV) and Atrial Septal Defect/Persistent Foramen Ovale (ASD/PFO). One point for each correct answer was awarded. Results: In our study participated 104 students. Mean score was 15.9 ± 5.8 points. 24% of participants were 3rd year students, 38% — 4th, 20% — 5th and 18% — 6th. Th ere was no diff erences in level of knowledge between students of diff erent years of studies (p = 0.2). Students from Students Research Groups (SRG) achieved higher score in comparison with students no attending SRG (19.3 ± 6.3 vs 13.3 ± 3.7; p <0.001) as well as students interested in cardiology comparison with other (19.6 ± 5.9 vs 13.0 ± 3.8; p <0.001). Students from SRG and interested in cardiology reached also higher results in practically every area of IC in comparison with other. Conclusions: Participants have insuffi cient, outdated and incomplete knowledge of new methods in IC. Th ere was no signifi cant diff erence in students of diff erent years of studies. Students belonging to cardiological SRG and interested in cardiology have greater knowledge in IC.
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Abstract

The interdisciplinary report is an effect of the work of a team of experts appointed by Division I for Humanities and Social Sciences, Polish Academy of Sciences (PAN). The team consisted of representatives of academic committees of the division. Its task was to formulate answers to 20 questions most frequently asked in public discourse regarding costs and benefits of the European integration, relations between Poland and the EU authorities, threats to the integration, the future of the EU and the place of Poland in the Community. The authors express concern about the potential results of the negative attitude of the current Polish government towards the actions of the institutions of the EU, the growing criticism towards the European integration and the threat of marginalisation of Poland within the EU or even the possibility of Poland’s leaving the EU (Polexit). They also indicate the possible economic, political and civilizational outcomes of the actions of the Polish authorities which weaken Poland’s ties to the EU. The report urges the academic community to increase their research activity and involvement in the public debate regarding these vital issues.
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Abstract

In these remarks I make an attempt to understand and present the functioning of authorities in science. I do use in the first place the earlier claims which present this issue in a historical perspective. This allows to grasp the social process of emergence of the authorities as well the changing of their position in the way they are functioning. Especially the thoughts of Max Weber are being considered by my as useful in this matter. I do share his general thesis saying that even the greatest of scientific authorities – called by me in these remarks ”centennial” – couldn't occur and function without their social and cultural ”background”. This had led in large extent to the situation where these authorities fist played a significant role in the development of science and then went over to a more or less dignified ”retirement”. In this and other issues I present some of my own remarks and sugestions.
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Abstract

The present paper discusses the new Polish law on higher education in the context of the contrasted global and academic paradigms of university funding, governance, and organization. Its point of departure is the advent of international comparative data in higher education, the measurability of individuals, academic units and institutions in terms of research output, and the emergence of a new social contract between the state and universities. The key concepts used to evaluate the new law are competition in science, academic income structure and academic knowledge production structure, internationalists and locals in science, and vertical differentiation in national higher education systems. The new law is assessed in the context of the original reform proposal suggested by the national team of experts led by the present author and its long-term strategic choices are discussed in more detail, including a changing system of institutional evaluation, a revised system of academic degrees, and new excellence-focused national funding schemes.
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Abstract

Empathy and psychopathy seem to be two distant extremes, which only differ, with nothing similar. Therefore, the question that seems to be surprising is whether such a theoretical perspective is justified. Empathy exerts significant influence on social relationships and is associated with moral development, whereas psychopathy seems to be an opposite phenomenon, as it is associated with the lack of deep interpersonal bonds and the violation of legal norms. As studies from various disciplines and scientific areas indicate, such concepts as behavioral effectiveness, morality or altruism might help explain the complex nature of the interrelationship between psychopathy and empathy. The authors tried to explore and describe the complexity of the two presented concepts in the light of the conducted research, and the resulting theoretical and empirical implications.
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Abstract

In the article the author discusses peculiarities of three areas of psychologists’ professional activity: conducting scientific research, educating new generations of psychologists, and having a private practice. He particularly stresses the significance of empirical testability of theories for correct and ethical assessment practice (according to Evidence-Based Assessment standard) and therapeutic practice (according to Evidence-Based Practice in Psychology standard). The author also explores the cultural immersion of psychological activity.
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Abstract

The cultivation of genetically modified crops has long been a contentious issue in the European Union. Now a group of biotech specialists and legal experts propose a mechanism to take the political edge out of the authorization process.
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Abstract

An outstanding Polish biochemist, laureate of the Foundation for Polish Science Prize in 2007, member of the Polish Academy of Sciences, a head of the Department of Molecular Biomedicine at the Institute of Bioorganic Chemistry, PAS in Poznan Professor Wlodzimierz Krzyzosiak’s research path led from the structural chemistry of nucleic acids, through molecular genetics and cancer genetics to molecular medicine. In the last years, Professor's scientific activity focused on understanding the role of RNA in the pathogenesis of human neurological diseases caused by the expansion of repetitive sequences. He also developed new methods of experimental therapy for this group of disorders using antisense oligonucleotides and RNA interference technology. He analyzed the factors influencing the microRNA biogenesis and used this knowledge to improve RNA interference technology tools in therapeutic approaches. Overall, Professor Krzyżosiak coauthored more than 130 publications, which have been cited more than 3500 times so far.
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Abstract

For centuries, identity has been an important existential issue, because it organizes human relation with the world. Identity is not only one man's being in a biological sense, but the principle of social and cultural order. The identity is the self-awareness, the result of the social actor's involvement in a variety of network connections which are forming a human being together with the biological dimension. Thus, the identity, on the one hand, is a kind of Erikson's tradition, namely the sense of being human, on the other hand interactionist tradition, modification of identity through a process of interaction. Contemporary world, the world of confronting cultures, raises the need for analysis of identity within many cultures, which has been shaped by continuous contact with different values, norms, patterns of behaviour. Upper Silesia has been our empirical reference point for the discussion on social (regional) identity. Identity of Upper Silesia is the result of a long and complicated history and present day. This identity is created by Polish, German, Czech and Jewish a cultural elements.
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