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Abstract

Introduction: Our umbrella review aimed to summarize and revisit the evidence from all of the meta-analyses and systematic reviews regarding the treatments of oropharyngeal squamous cell carci-noma (OPSCC).
Materials and Methods: Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, Cochrane Library, BIOSIS, and EBSCO were searched. The overall search process was conducted in 3 stages.
Results: Finally, a total of 28 studies met the inclusion criteria and were included in this study. Out of those 28 meta-analyses, a total of 315 primary studies were screened in order to extract the data and perform the statistical analysis. In total, data from 22,619 patients was analyzed.
Conclusion: The main objective of the present umbrella review was to summarize and analyze all of the evidence-based data provided by numerous meta-analyses and systematic reviews regarding the treatment of OPSCC. Our study delivers the most up-to-date and evidence-based results regarding the different therapeutic modalities of this malignancy in one concise review, making it the ultimate tool for physicians treating OPSCC.
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Authors and Affiliations

Dawid Plutecki
1
Elżbieta Szczepanek
2 3
Małgorzata Szczepanek
2
Ameen Nasser
4
Paweł Hajdyła
4
Paweł Wrona
4

  1. Collegium Medicum, Jan Kochanowski University, Kielce, Poland
  2. Department of Otolaryngology and Head and Neck Surgery, Medical University of Warsaw, Warsaw, Poland
  3. Doctoral School in Medical Sciences and Health Sciences, Jagiellonian University Medical College, Kraków, Poland
  4. Department of Anatomy, Jagiellonian University Medical College, Kraków, Poland
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Abstract

The dorsal capsule of the wrist and the DCSS may play a significant role in the conduction of nerve signals transmitted from proprioceptors present in SL to PIN, which is located above the dorsal capsule. Hence, this study aimed to determine if nerve fibers of PIN penetrate inside the dorsal capsule. The dorsal capsules of the wrist were dissected from both sides from 15 cadavers. Eventually, 30 dorsal capsules were dissected. It can be concluded that the PIN nerve fibers penetrate the dorsal capsule of the wrist, as the penetration was noticeable in every part evaluated.
The present study proves that afferent fibers from the mechanoreceptors of the SLIL potentially pass through the DCSS and subsequently through the dorsal capsule of the wrist to the PIN. This knowledge can surely be of great use for hand surgeons that perform procedures on the dorsal wrist.
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Authors and Affiliations

Michał Bonczar
1
Tomasz Bonczar
1
Patryk Ostrowski
1
Martyna Dziedzic
1
Mariusz Bonczar
1
Dawid Plutecki
2
Anna Gil
1
Małgorzata Jasińska
3
Grzegorz Lis
3
Jerzy Walocha
1
Mateusz Koziej
1

  1. Department of Anatomy, Jagiellonian University Medical College, Kraków, Poland
  2. Collegium Medicum, Jan Kochanowski University, Kielce, Poland
  3. Department of Histology, Jagiellonian University Medical College, Kraków, Poland
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Abstract

Introduction: The main goal of the present umbrella review was to provide the most up-to- date and evidence-based results regarding the various treatment options for tennis elbow (TE), which hopefully will significantly decrease the confusions existing in the literature. Furthermore, our study differs from past analytical studies because, as to the best of the authors’ knowledge, is the first to provide independent (not in comparison to other treatment) statistical results regarding the effectiveness of each TE treatment.
Materials and Methods: Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, Cochrane Library, BIOSIS, and EBSCO were searched. The overall search process was conducted in 3 stages.
Results: A total of 40 studies met the inclusion criteria and were included in this study. Out of those 40 meta-analyses, a total of 160 primary studies were screened in order to extract the data and perform a statistical analysis.
Conclusion: The present umbrella review underlines the efficiency of injection therapies, especially autologous blood, and platelet-rich plasma, while simultaneously proving the ineffectiveness of acupunc-ture and shock wave therapy as treatments for TE. Furthermore, the value of other known conservative treatment modalities, such as physical therapy, has been demonstrated.
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Authors and Affiliations

Michał Bonczar
1 2
Patryk Ostrowski
1 2
Dawid Plutecki
2 3
Martyna Dziedzic
1 2
Jakub Florek
4
Weronika Michalik
1
Wojciech Przybycień
1
Paweł Depukat
1
Bartosz Rutowicz
1
Ewa Walocha
1 2
Mateusz Koziej
1 2

  1. Department of Anatomy, Jagiellonian University Medical College, Kraków, Poland
  2. Youthoria. Youth Research Organization, Kraków, Poland
  3. Collegium Medicum, Jan Kochanowski University, Kielce, Poland
  4. Department of Orthopaedics and Traumatology, Rydygier Hospital, Brzesko, Poland

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