The article presents the results of experiments on a detection system used for detecting signals from a miniature, low-energy micro-electro-mechanical system (MEMS) X-ray source. The authors propose to use a detection based on luminescence phenomena occurring in luminophore and scintillators to record the visual signal on a CMOS/CCD detector. The main part of the article is a review of various materials of scintillators and luminophores which would be adequate to convert low-energy X-ray radiation (E < 25 keV – it is a range not typical for conventional X-ray systems) to visible light. Measurements obtained for different energies, exposure times, and different targets have been presented and analysed.