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Abstract

When designing injectable scaffolds for biomedical applications, it is crucial to determine the conditions for the formation of unlimited structures, in particular the kinetics at constant temperature. Despite many studies, these conditions have not been characterized so far after injection, which is such an important application aspect. The aim of the research is to discuss the impact of the injection application on the polymer structure and to propose new criteria for assessing the potential of thermosensitive biopolymer sols, considering the flow under high shear rates during the administration.
Based on the analysis of the obtained results of rheological tests, it was shown that the flow through the needles causes a significant change in the elastic properties that define the polymer structure, with almost unchanged viscous properties. As a consequence, the parameters characterizing the polymer coil change, which, combined with the quantitatively proven fragmentation, indicates that injection application may affect the size of the coils that will not reach the critical size of the aggregating nucleus.
Finally, extended research procedures for the conscious design of injectable scaffolds are proposed as well as key rheological parameters to ensure thermoinduced aggregation preceded by shear during injection are provided.
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Authors and Affiliations

Anna Rył
1
ORCID: ORCID
Piotr Owczarz
1
ORCID: ORCID

  1. Department of Chemical Engineering, Lodz University of Technology, Wolczanska 213, 93-005 Lodz
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Abstract

We propose a spit bar setting as the possible palaeoenvironment of the basal Late Cretaceous transgressive sequence in NW Bohemia. A new Cenomanian transgression model for the Bohemian Basin is also proposed. The uppermost Devět Křížů Sandstone, which has been conventionally referred to the Bohdašín Formation, probably represents the middle or lower upper Cenomanian (Upper Cretaceous), not the Triassic as previously supposed. We assume that this controversial unit was deposited before the main latest Cenomanian–early Turonian transgression. The spit bars were likely overgrown by vascular plants during their emergence in the late Cenomanian, and then inundated during the latest Cenomanian and early Turonian transgressive phases. The studied deposits had been intensively bioturbated, and the cf. Taenidium suite was recognized for the first time in them alongside the Thalassinoides assemblage (T. paradoxicus, T. suevicus, Thalassinoides isp., cf. Thalassinoides), which are characteristic of the Scoyenia and Glossifungites ichnofacies, respectively. The bioturbated, rhizolith-bearing horizon was presumably a paleosol.
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Authors and Affiliations

Alina Chrząstek
1
Jurand Wojewoda
2

  1. Institute of Geological Sciences, University of Wrocław, Maksa Borna 9, 50-204 Wrocław, Poland
  2. Faculty of Geoengineering, Mining and Geology, Wrocław University of Science and Technology,Na Grobli 15, 50-421 Wrocław, Poland

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