The paper presents numerical and experimental research on glulam delamination in a double lap connection with predominant shear stresses. Laboratory tests and wide literature survey enabled to determine timber and glue joint parameters. Cohesive zone theory, generally used for epoxy matrix and fiber reinforced composites, was adopted to modelling glue layer delamination in glulam elements. Numerical models were validated with laboratory tests.

Objective: Evaluation of serum lactadherin level, its correlation with disease activity and certain biochemical parameters in IBD patients.
Methods: The study involved adult IBD patients, comprising 50 with ulcerative colitis (UC), 68 with Crohn’s disease (CD), and 29 healthy controls.
Results: The MFGE8 median concentration was significantly higher in UC versus controls (1914.54 vs. 1392.21; p = 0.017), but not in CD. The median MFGE8 levels in UC and CD patient groups didn’t significantly differ. There was a significant inverse correlation between MFGE8 and CRP (r = –0.283; p = 0.044) and fibrinogen (r = –0.362, p = 0.017) in UC. In active UC, MFGE8 median concentration was higher versus controls (1974.36 vs. 1392.21; p = 0.04) and negatively correlated with CRP (r = –0.482; p = 0.005), WBC (r = –0.391; p = 0.027), and fibrinogen (r = –0.473; p = 0.015). Inactive UC showed negative correlation only with fibrinogen (r = –0.567; p = 0.018). No correlations were found with disease activity measured using appropriate scales, age, BMI, or gender.
Conclusions: Active UC patients show higher MFGE8 levels. These increase inversely with inflamma-tory markers (CRP, WBC, fibrinogen) in active UC, but not in CD.