Search results

Filters

  • Journals
  • Authors
  • Keywords
  • Date
  • Type

Search results

Number of results: 2
items per page: 25 50 75
Sort by:
Download PDF Download RIS Download Bibtex

Abstract

In this study, it was aimed to investigate the effect of hip dysplasia on some biochemical parameters, oxidative stress factors and hematocrit values in dogs. Hematocrit values (HTC), serum calcium (Ca), phosphorus (P) levels, serum alkaline phosphatase (ALP), creatine kinase (CK) activities and oxidative stress factors were evaluated in a total of 27 dogs with healthy hip joints (n: 11) and hip dysplasia (n: 16). There was no statistically significant difference between the two groups in terms of HCT, Ca and P values (p˃0.05). ALP and CK activities were found to be statistically significantly increased in the group with hip dysplasia compared to the control group with a healthy hip joint (p˂0.05). While malondialdehyde (MDA) level, one of the oxidative stress factors, was increased in the group with hip dysplasia, decreased glutathione (GSH) levels, catalase (CAT) and glutathione peroxidase (GSH-Px) activities were significantly decreased. There was no significant difference between the two groups in terms of superoxide dismutase (SOD) level. As a result, it was determined that oxidative stress factors differ in dogs with hip dysplasia compared to dogs with the healthy hip joint.
Go to article

Bibliography


Aebi H (1984) Catalase. Methods Enzymol 105: 121-126.

Ajadi AR, Sanni JL, Sobayo EF, Ijaopo K (2018) Evaluation of plasma trace elements and oxidant/antioxidant status in Boerboel dogs with hip dysplasia. Bulg J Vet Med 23: 1-11.

Altıner A, Atalay H, Bilal T (2018) Free radicals and the relationship with stress. Balikesir Health Sci J 7: 51-55.

Bakır B, Büyükönder H, Özer K, Belge A (1992) Studies on blood serum alkaline phosphatase enzyme activity in hip dysplasia and normal sivas kangal dogs. Proceedings of the 3rd National Veterinary Surgery Congress, pp 64-70.

Beutler E (1984) Red cell metabolism. A manual of biochemical methods. 2nd ed., Grune and Starton, New York: 160.

Birben E, Şahiner UM, Sackesen C, Erzurum S, Kalayci O (2012) Oxidative stress and antioxidant defense. World AO J 5: 9-19.

Bostancı B, Demirkan I (2017) Determination of Prevalance of Canine Hip Dysplasia By Pennhip Method. Kocatepe Vet J 10: 269-277.

Candas A (1982) Hip dysplasias in dogs. Vet J AU 29: 235-248.

Çaptug Ö, Bilgili H (2007) Current Approaches of Canine Hip Dysplasia Part II: Clinical Diagnosis of Canine Hip Dysplasia. J Fac Vet Med Univ Erciyes 4(1): 35-42.

Dassler CL (2002) Canine hip dysplasia: Diagnosis and nonsurgical treatment. In: Slatter D, Textbook of Small Animal Surgery. 3rd ed., Saunders, Philadelphia, 2019-2029.

Denny HR, Buerworth S (2000) The Hip. In: A guide to canine and feline orthopaedic surgery. 4 ed., Blackwell Science, London: pp 455-494.

Ellman GL, Courtney KD, Andres V Jr, Feather-stone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7: 88-95.

Frankel S, Reitman S, Sonnen AC (1970) A textbook on laboratory procedure and their interpretation. Grand-Wohl’s clinical laboratory methods and diagnosis. Mosby Co, London, pp 403-404.

Ginja MMD, Ferreira AJA, Silvestre AM, Gonzale-Orden JM, Llorens-Pena MP (2006) Hip joint fluid and passive laxity in puppies at 7 or 8 weeks of age and its correlation with late hip laxity and canine hip dysplasia. 13th ESVOT Congress. September, 7-10, Munich, Germany, pp 232-233.

Karabaglı M, Olgun- Erdikmen D, Özer K (2014) Diagnosis and Treatment Options in Hip Dysplasia. Türkiye Klinikleri J Vet Sci 5: 54-61.

Lust G, Rendano VT, Summers BA (1985) Canine hip dysplasia: concepts and diagnosis. J Am Vet Med Assoc 187(6): 638-640.

Mukherjee S, Ghosh S, Choudhury S, Adhikary A, Manna K, Dey S, Sa G, Das T, Chattopadhyay S (2013) Pomegranate reverses metho-trexate-induced oxidative stress and apoptosis in hepatocytes by modulating Nrf2-NF-κB pathways. J Nutr Biochem 24: 2040-2050.

Or ME, Gülanber EG, Kalınbacak A, et al. (2001) The correlations of some serum parameters and hip dysplasia on Turkish Shepherd (Sivas Kangal) and German Shepherd dogs. Acta Veterinaria Eurasia 27: 469-476.

Placer ZA, Cushman L, Johnson BC (1966) Estimation of products of lipid peroxidation in biochemical systems. Anal Biochem 16: 359-364.

Prasad AS (1978) Trace elements and iron in human metabolism. John Willey and Sons, NY.

Polat E (2021) Hip dysplasia in dogs. Veterinary Medicine and a New Look at Beekeepıng. 1st ed., IKSAD Publishing House, Ankara, pp 41-74.

Sarı H, Bilgili H (2011) Evaluation of Norberg-Olsson and distraction index hip joint angles measurement using with a new computerized programme on canine hip dysplasia. Vet Hek Der Derg 82: 49-58.

Schachner ER, Lopez MJ (2015) Diagnosis, prevention, and management of canine hip dysplasia: A review. Vet Med Res Rep 6: 181-192.

Sharma U, Pal D, Prasad R (2014) Alkaline phosphatase: An overview. Indian J Clin Biochem 29: 269–278.

Sun Y, Oberley LW, Li Y (1988) A simple method for clinical assay of superoxide dismutase. Clin Chem 34: 497-500.

Szilagyi M, Sagi L (1976) Bone mineral contents and serum alkaline phosphatase activity of healthy and hip dysplasic German Sheep dogs. Acta Vet Acad Sci Hung 25: 297-301.

Teixeira AM, Borges GF (2012) Creatine kinase: structure and function. Brazi J Biomotr 6: 53-65.

Wallace LJ (1987) Canine hip dysplasia: Past and present. Semin Vet Med Surg 2: 92-106.

Zilva FJ, Pannal PR (1975) Clinical Chemistry in Diagnosis and Treatment, 2nd ed., Lloyd-Luke LTD, London.
Go to article

Authors and Affiliations

E. Polat
1
M.C. Han
1
E. Kaya
2
S. Yilmaz
2
S.D. Kayapinar
1
S. Coskun
1
A. Yildirim
1
U.K. Can
1

  1. Fırat University, Faculty of Veterinary Medicine, Department of Surgery, Elazig, Turkey
  2. Fırat University, Faculty of Veterinary Medicine, Department of Biochemistry, Elazig, Turkey

This page uses 'cookies'. Learn more