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Abstract

The short outlook at main problems related to pollutant migration modelling in the granular layer is critically discussed in the paper. The general model of pollutant migration in granular was transposed into dimensionless form. The general model was adapted to describe the examined decontamination technology and two operational models were differentiated due to the dominant mass transfer resistances in the system. The verification validated the functional effectiveness of the suggested model and its numerical implementation under different conditions. It approves the possibility of the practical application of the proposed method. The problem of influence of irregular distribution of negative mass sources (sorptivc agglomerates) on mass transport in the granular layer was underlined.
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Authors and Affiliations

Anna Adach
Stanisław Wroński
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Abstract

The investigations deal with mass transfer in simulated biomedical systems. The modification of classical diffusion chamber, sequential unit (SU) system, imitated different biomedical setups, boundary conditions. The experiments simulated: diffusion chamber (also with two barriers), transport through the membrane to the blood stream, transport from the stent eluting drug simultaneously to the vessel cells and to the blood stream. The concentrations of substances and the relative mass increases/decreases for SU systems indicate that the order of the curves follows the order of mass transfer resistances. The strong dependence of mass transfer rates versus type of diffusing substance was confirmed. The calculated drug fluxes, diffusion coefficients, permeation coefficients are convergent with literature. Permeation coefficients for complex sequential systems can be estimated as parallel connexion of constituent coefficients. Experiments approved functionality of the SU for investigations in a simulated biomedical system. Obtained data were used for numerical verification.

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Authors and Affiliations

Anna Adach
Natalia Kister
Andrzej Skassa
Aleksandra Bugalska

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