Abstract
Cutaneous adverse food reaction (CAFR) is a common disease, affecting about 1-2% of dogs and cats. Diagnosis of the CAFR is made through elimination diet coupled with diet challenge, as methods like skin tests, patch tests, basophil degranulation tests and assessment of IgG and IgE serum levels are not sensitive enough. A partially hydrolysed salmon and pea hypoallergenic diet was evaluated in the diagnosis and treatment of CAFR in dogs and cats.
The diet was used in the treatment of 13 dogs and 12 cats for 10 weeks. The Pruritus Visual Analog Scale (PVAS; dogs and cats), Canine Atopic Dermatitis Extent and Severity Index (CADESI-04; dogs) and the Scoring Feline Allergic Dermatitis (SCORFAD; cats) were used for effectiveness evaluation.
In dogs, a significant decrease was reported in both CADESI-04 (from 17.3±7.5 to 10.15±7.4; p=0.028) and PVAS (from 7±1.3 to 4.76±1.8; p=0.003) after four weeks of treatment. Also in cats, both the PVAS (from 6.75±1.8 to 4±2.3; p=0.006) and SCORFAD (from 4.16±1.9 to 2.58±1.2; p=0.029) decreased significantly after four weeks. After eight weeks, a significant improvement was observed in almost all the animals. Evaluated diet was useful in the treatment of the CAFR in dogs and cats.
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Bibliography
Alexander DD, Schmitt DF, Tran NL, Barraj LM, Cushing CA (2010) Partially hydrolyzed 100% whey protein infant formula and atopic dermatitis risk reduction: a systematic review of the literature Nutr Rev, 68: 232-245.
Anderson JA (1986) The establishment of common language concerning adverse reactions to foods and food additives J Allergy Clin Immunol, 78: 140-144.
Belova S, Wilhelm S, Linek M, Beco L, Fontaine J, Bergvall K, Favrot C (2012) Factors affecting allergen-specific IgE serum levels in cats Can J Vet Res, 76: 45-51.
Bethlehem S, Bexley J, Mueller RS (2012) Patch testing and allergen-specific serum IgE and IgG antibodies in the diagnosis of canine adverse food reactions Vet Immunol Immunopathol, 145: 582-589.
Biourge VC, Fontaine J, Vroom MW (2004) Diagnosis of Adverse Reactions to Food in Dogs: Efficacy of a Soy-Isolate Hydrolyzate-Based Diet J Nutr, 134 (Suppl): 2062S-2064S.
Chesney CJ (2002) Food sensitivity in the dog: a quantitative study J Small Anim Pract, 43: 203-207.
DeBoer DJ, Hillier A (2001) The ACVD task force on canine atopic dermatitis (XV): Fundamental concepts in clinical diagnosis. Vet Immunol Immunopathol, 81: 271-276.
Denis S, Paradis M (1994) L’allergie alimentaire chez le chien et le chat. Le Médecin Vétérinaire Du Québec, 24: 15-20
Favrot C, Linek M, Fontaine J, Beco L, Rostaher A, Fischer N, Couturier N, Jacquenet S, Bihain BE (2017) Western blot analysis of sera from dogs with suspected food allergy Vet Dermatol, 28: 189-e42.
Favrot C, Steffan J, Seewald W, Hobi S, Linek M, Marignac G, Olivry T, Beco L, Nett C, Fontaine J, Roosje P, Bergvall K, Belova S, Koebrich S, Pin D, Kovalik M, Meury S, Wilhelm S (2012) Establishment of diagnostic criteria for feline nonflea-induced hypersensitivity dermatitis. Vet Dermatol 23(1): 45-50. Favrot C, Steffan J, Seewald W, Picco F (2010) A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol, 21: 23-31.
Foster AP, Knowles TG, Moore AH, Cousins PDG, Day MJ, Hall EJ (2003) Serum IgE and IgG responses to food antigens in normal and atopic dogs, and dogs with gastrointestinal disease. Veter Immunol Immunopathol, 92: 113-124.
Guilford WG (1996) Gastorintestinal immune system. In: Guilford WG, Center SA, Strombeck DR (eds) Strombeck’s small animal gastroenterology. Philadelphia, W.B. Saunders Co. pp 20-37.
Guilford WG, Jones BR, Markwell PJ, Arthur DG, Collett MG, Harte JG (2001) Food Sensitivity in Cats with Chronic Idiopathic Gastrointestinal Problems. J Vet Intern Med 15(1): 7.
Hill PB, Lau P, Rybnicek J (2007) Development of an owner- -assessed scale to measure the severity of pruritus in dogs. Vet Dermatol 18: 301-308.
Jackson HA, Jackson MW, Coblentz L, Hammerberg B (2003) Evaluation of the clinical and allergen specific serum immunoglobulin E responses to oral challenge with cornstarch, corn, soy and a soy hydrolysate diet in dogs with spontaneous food allergy. Vet Dermatol 14: 181-187.
Jeffers JG, Shanley KJ, Meyer EK (1991) Diagnostic testing of dogs for food hypersensitivity. J Am Vet Med Assoc 198: 245-250.
Martin A, Sierra MP, Gonzalez JL, Arevalo MA (2004) Identification of allergens responsible for canine cutaneous adverse food reactions to lamb, beef and cow’s milk. Vet Dermatol 15: 349-356.
Mueller RS, Olivry T, Prélaud P (2016) Critically appraised topic on adverse food reactions of companion animals (2): common food allergen sources in dogs and cats. BMC Vet Res 12: 9.
Mueller RS, Tsohalis (1998) Evaluation of serum allergen- -specific IgE for the diagnosis of food adverse reactions in the dog. Vet Dermatol 9: 167-171.
Olivry T, Mueller RS (2016) Critically appraised topic on adverse food reactions of companion animals (3): prevalence of cutaneous adverse food reactions in dogs and cats. BMC Vet Res 13: 51.
Olivry T, Mueller RS (2020) Critically appraised topic on adverse food reactions of companion animals (9): time to flare of cutaneous signs after a dietary challenge in dogs and cats with food allergies. BMC Vet Res 16: 158.
Olivry T, Saridomichelakis M, Nuttall T, Bensignor E, Griffin CE, Hill PB (2014) Validation of the Canine Atopic Dermatitis Extent and Severity Index (CADESI)-4, a simplified severity scale for assessing skin lesions of atopic dermatitis in dogs. Vet Dermatol 25: 77-e25.
Ricci R, Hammerberg B, Paps J, Contiero B, Jackson H (2010) A comparison of the clinical manifestations of feeding whole and hydrolysed chicken to dogs with hypersensitivity to the native protein. Vet Dermatol 21: 358-366.
Rosser EJ (2013) Diagnostic Workup of Food Hypersensitivity. In: Noli C, Foster A, Rosenkrantz W (ed), Veterinary Allergy. Wiley Blackwell, Oxford pp. 119-123.
Rosser EJ (1993) Diagnosis of food allergy in dogs. J Am Vet Med Assoc, 203: 259-262.
Roudebush P, Guilford WG, Shanley KJ (2000) Adverse reactions to food. In: Hand MS, Novotny BJ (eds) Small animal clinical nutrition. Mark Morris Institute pp 431-453.
Rybníček J, Lau-Gillard PJ, Harvey R, Hill PB (2009) Further validation of a pruritus severity scale for use in dogs. Vet Dermatol 20: 115-122.
Scott DW, Miller WH, Griffin CE (2001) Muller & Kirk’s Small Animal Dermatology. In: Scott DW, Miller WH, Griffin CE (eds) Muller & Kirk’s Small animal dermatology. Saunders pp 543-666.
Steffan J, Olivry T, Forster SL, Seewald W (2012) Responsiveness and validity of the SCORFAD, an extent and severity scale for feline hypersensitivity dermatitis. Vet Dermatol 23: 410-e77.
Walton GS (1967) Skin responses in the dog and cat to ingested allergens. Observations on one hundred confirmed cases. Vet Rec 81: 709-713. White SD (1986) Food hypersensitivity in 30 dogs. J Am Vet Med Assoc 188: 695-698.
White SD, Sequoia D (1989) Food hypersensitivity in cats: 14 cases (1982-1987). J Am Vet Med Assoc, 194: 692-695. Wills J, Harvey R (1994) Diagnosis and management of food allergy and intolerance in dogs and cats. Austr Vet J 71: 322-326.
Zimmer A, Bexley J, Halliwell RE, Mueller RS (2011) Food allergen-specific serum IgG and IgE before and after elimination diets in allergic dogs. Vet ImmunolImmunopathol 144: 442-447.
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