This paper presents a study on the dry turning of polyoxymethylene copolymer POM-C. The effect of five factors (cutting speed, feed rate, depth of cut, nose radius, and main cutting edge angle) on machinability is evaluated using four output parameters: surface roughness, tangential force, cutting power, and material removal rate. To do so, the study relies on three approaches: (i) Pareto statistical analysis, (ii) multiple linear regression modeling, and (iii) optimization using the genetic algorithm. To conduct the investigation, mathematical models are developed using response surface methodology based on the Taguchi L16 orthogonal array. The results indicate that feed rate, nose radius, and cutting edge angle significantly influence surface quality, while depth of cut, feed, and speed have a notable impact on other machinability parameters. The developed mathematical models have determination coefficients greater than or very close to 95%, making them very useful for the industry as they allow predicting response values based on the chosen cutting parameters. Finally, the optimization using the genetic algorithm proves to be promising and effective in determining the optimal cutting parameters to maximize productivity while improving surface quality.