In this contribution an optical method of controlling the state of soft biological tissues in real time, exposed to laser radiation is discussed. The method is based on the assumption that the change dynamics of the amplitude of the scattered diagnostic radiation (λ = 635 nm) is compatible with the change dynamics of the tissue inner structure exposed to the Nd:YAG laser radiation (λ = 1064 nm). In this method the measurement of the tissue temperature is omitted. Exemplary results of the laboratory research on this method and an interpretation of the results are presented.