Traditional methods of mineral exploration are mainly based on very expensive drilling and seismic methods. The proposed approach assumes the preliminary recognition of prospecting areas using satellite remote sensing methods. Maps of mineral groups created using Landsat 8 images can narrow the search area, thereby reducing the costs of geological exploration during mineral prospecting. This study focuses on the identification of mineralized zones located in the southeastern part of Europe (Kosovo, area of Selac) where hydrothermal mineralization and alterations can be found. The article describes all the stages of research, from collecting in-situ rock samples, obtaining spectral characteristics with laboratory measurements, preprocessing and analysis of satellite images, to the validation of results through field reconnaissance in detail. The authors introduce a curve-index fitting technique to determine the degree of similarity of a rock sample to a given pixel of satellite imagery. A comparison of the reflectance of rock samples against surface reflectance obtained from satellite images allows the places where the related type of rock can be found to be determined. Finally, the results were compared with geological and mineral maps to confirm the effectiveness of the method. It was shown that the free multispectral data obtained by the Landsat 8 satellite, even with a resolution of 30 meters, can be considered as a valuable source of information that helps narrow down the exploration areas.