The purpose of the studies was to estimate efficiency of delivering nebulised drugs into the lower respiratory tract through endotracheal tubes (ET tubes) which are commonly used in the treatment of uncooperative patients. Water solution of Disodium Cromoglycate (DSCG) was nebulised with a constant air flow (25 l/min). Experimental studies were done for eight ET tubes with varying sizes (internal diameter, length) and made of two different materials. Size distribution of aerosol leaving ET tubes was determined with the use of aerosol spectrometer. Fine Particle Fraction (FPF) and Mass Median Aerodynamic Diameter (MMAD) were calculated for the aerosol leaving each tube. Additionally, mass of the Disodium Cromoglycate deposited into each endotracheal tube was determined. ET tubes can significantly influence the parameters of delivered aerosol depending on their diameter. FPF of aerosol delivered in to the respiratory tract is lower if small endotracheal tubes are used. However, MMAD and FPF for large endotracheal tubes are almost identical with MMAD and FPF from nebuliser. The results indicate that a substantial fraction of large droplets is eliminated from the aerosol stream in long endotracheal tubes (270 mm). In this case the mass of drug delivered through ET tubes is reduced but the content of small droplets increases (high value of FPF).
This study attempted to manufacture an Y2O3 ceramic coating layer on a ceramic (AlN) substrate using aerosol deposition (AD) and investigated its macroscopic properties. Pure Y2O3 powder with a polygonal shape and average size of 5.0 μm was used as initial feedstock. Using aerosol deposition with suitable process conditions, an Y2O3 coating layer was successfully fabricated on aluminum nitride (AIN). The thickness of the manufactured coating layer was approximately 10 mm. The coating layer consisted of Y2O3 phase identical to that in the initial powder, and no additional oxides were identified. In regard to the roughness of the Y2O3 coating layer, the average roughness (Ra) measured 1.32 μm, indicating that the surface roughness was relatively even compared to the initial powder size (5 μm). Mechanical properties of the Y2O3 coating layer were measured using nano indentation equipment, and the indentation modulus of the Y2O3 coating layer fabricated by aerosol deposition measured 136.5 GPa. The interface of the coating layer was observed using TEM, and the deposition mechanism of the Y2O3 coating layer manufactured by aerosol deposition was also discussed.
The risk of human exposure to finely-dispersed aerosol particles being airborne indoors is determined by the size and the number concentration of particles, the intensity of an aerosol emission source, the air filtration and ventilation efficiency, etc. The emphasis in this article is on behaviour patterns of aerosol particles when exposed to ultrasonic and electrostatic fields in different conditions of air temperature and relative humidity. Wood flour having sizes of interest (characteristic particle diameter about 10 μm) is chosen as a model aerosol. The article considers a physical and mathematical model presenting the evolution of aerosol particles in external fields, taking into account the moisture content and the temperature of a dispersive medium. The efficiency of ultrasonic and electrostatic precipitation in different relative humidity and temperature conditions in an enclosed space was studied using optical measurement methods of particle size and concentration.
Range-gated-imaging system, which can be used to eliminate backscatter in strong scattering environments, is based on two high speed technologies. It uses high power, ultra-short pulse laser as the light source. And it opens the optical gate of an ICCD camera with a micro-channel-plate image intensifier in a very short time while the laser pulses reflected by the object is coming back to the ICCD camera. Using this range-gated-imaging technology, the effect of scattered light can be reduced and a clear image is obtained.
In this paper, the test results of the range-gated-imaging system under dense aerosol environments, which simulates environments in the reactor containment building when the severe accident of the nuclear power plant occurred, are described. To evaluate the observation performance of the range-gated-imaging system under such dense fog environment, we made a test facility. Fog particles are sprayed into the test facility until fog concentration is reached to the postulated concentration level of the severe accident of the nuclear power plant. At such dense fog concentration conditions, we compared and evaluated the observation performances of the range-gated-imaging system and the CCD camera.
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