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Abstract

Due to an increasing amount of music being made available in digital form in the Internet, an automatic organization of music is sought. The paper presents an approach to graphical representation of mood of songs based on Self-Organizing Maps. Parameters describing mood of music are proposed and calculated and then analyzed employing correlation with mood dimensions based on the Multidimensional Scaling. A map is created in which music excerpts with similar mood are organized next to each other on the two-dimensional display.
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Authors and Affiliations

Magdalena Plewa
Bożena Kostek
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Abstract

Reticuloendotheliosis virus (REV) is an avian oncogenic retrovirus that causes atrophy of immune organs, such as the spleen, thymus, and bursa of Fabricius, leading to severe immunosuppression. However, there is limited information describing the genes or microRNAs (miRNAs) that play a role in replicating REV-spleen necrosis virus (SNV). Our previous miRNA and RNA sequencing data showed that the expression of gga-miR-222b-5p was significantly upregulated in REV-SNV-infected chicken spleens of 7, 14, and 21 dpi compared to non-infected chicken spleens, but mitogen-activated protein kinase 10 (MAPK10), which is related to innate immunity, had the opposite expression pattern. To understand chicken cellular miRNA function in the virus-host interactions during REV infection, we used quantitative reverse transcription PCR (qRT-PCR) to determine whether the expression of gga-miR-222b-5p and MAPK10 in the spleen of specific-pathogen-free chickens at 28, 35, and 42 dpi was consistent with the first 3 time points, and dual-luciferase reporter assay was used to determine the targeting relationship between gga-miR-222b-5p and MAPK10. Results show that MAPK10 was downregulated at all 3 time points; however, significant difference (p<0.01) was noted only at 35 dpi. Moreover, the expression of gga-miR-222b-5p was upregulated; however, significant difference (p<0.01) was observed only at 28 and 35 dpi. A dual-luciferase reporter assay showed that MAPK10 is a direct target of gga-miR-222b-5p. This study suggests that gga-miR-222b-5p may target MAPK10 to promote the REV-SNV-induced tumorigenesis via the RLRs signaling pathway.
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Bibliography


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Authors and Affiliations

H. Jiang
1 2 3
S. Gao
4
M. Mao
1 2 3
Y. Diao
1 2 3
Y. Tang
1 2 3
J. Hu
1 2 3

  1. College of Veterinary Medicine, Shandong Agricultural University, No.61 Daizong Street, Tai’an 271018, China
  2. Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, No.61 Daizong Street, Tai’an 271018, China
  3. Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Shandong Agricultural University, No.61 Daizong Street, Tai’an 271018, China
  4. Unit of Animal Infectious Diseases, State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, No.1 Shizi Shan Street, Wu’han 430070, China
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Abstract

This volume, a collection of articles by Svetlana Tolstaya, is representative of the Moscow ethnolinguistic school, whose main goal (as was the intention of its founder, Nikita I. Tolstoy) is to reconstruct the spiritual ancestry of Slavs from both historical data and contemporary dialectological and ethnographic records. The rich and varied achievements of the Moscow ethnolinguistic school and specifically Svetlana Tolstaya are reviewed here, along with her contribution to building Polish‑Russian scholarly cooperation. The examples of mir, sud'ba, *svojь are used to illustrate the advantages of the analytical method employed by the author, i.e. semantic reconstruction within semantic microfields.
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Bibliography

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Authors and Affiliations

Jerzy Bartmiński
1 2
ORCID: ORCID

  1. Instytut Filologii Polskiej UMCS, Lublin
  2. Instytut Slawistyki PAN, Warszawa

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