Tooth loss extends beyond oral health concerns, impacting overall well-being and quality of life. It is a global issue, with approximately 7% of individuals aged 20 years or older affected. Research reveals associations between tooth loss and cardiovascular diseases, including hypertension, atherosclerosis, and peripheral arterial disease, attributed mainly to chronic inflammation and altered dietary habits. However, tooth loss has also been associated with cognitive decline, depression, and certain cancers, including lung, head and neck, pancreatic, and esophageal, suggesting the involvement of complex pathophysiological mechanisms that are increasingly the subject of experimental research. In addition, there are psychosocial consequences, such as self-esteem issues and social discomfort. Therefore, it is indisputable that comprehensive oral care is of utmost importance. Recognizing the importance of oral health for overall well-being highlights the necessity for preventative measures and enhanced dental care. As the global population ages, it is increasingly important to comprehend and address the systemic effects of tooth loss. This review aims to summarize the complex pathomechanisms underlying tooth loss and emphasize the need for a comprehensive approach to address its diverse consequences. It advocates for preventive oral health measures to sustain general health and well-being.

Introduction: An endoscopic intragastric balloon (IGB) placement is one of the minimally invasive methods of obesity treatment. One of the rare serious complications is mechanical bowel obstruction requiring operative management. We report a case of a male patient with small bowel obstruction due to IGB migration and the literature review of complications during IGB treatment. Detailed Case Description: A patient with a BMI of 28 kg/m2 was admitted to the hospital with spontaneous deflation of an IGB. Due to the suspected location of IGB in the ileum laparoscopy was performed. The enterotomy was performed and the IGB removed. The procedure and the postoperative period were uneventful. Discussion: Spontaneous IGB ruptures are reported in the literature with a frequency ranging from 0.6 to 23%. The majority of deflated devices are spontaneously excreted with the stool with no abdominal symptoms. Only 0.38% of IGBs cause mechanical bowel obstruction of requiring surgical management. Based on our own experience and literature review, we propose the diagnostic and therapeutic algorithm. Conclusion: Complications after IGB placement can range from mild to severe, that is why it is so important to make an early diagnosis based on the emerging symptoms and to implement prompt management to reduce or avoid serious complications. Any patient reporting disturbing symptoms occurring over a prolonged period of time requires hospitalization and careful observation for the occurrence of gastrointestinal obstruction. The ideal option is hospitalization in the center which implemented the IGB and start with the algorithm we proposed.

Herein we present the fatal case of premature baby with coincidence of extreme form of ectopia cordis and hypoplastic left heart structures

Background: Kidney diseases are a major global health problem affecting millions of people. Despite this, there is as yet no effective drug therapy improving outcome in patients with renal disease. The aim of this study was to examine the nephroprotective effect of α-lipoic acid (ALA) in vitro and to examine the effect of ALA administered in vivo on the production of reactive sulfur species (RSS), including hydrogen sulfide (H2S) and compounds containing sulfane sulfur. Methods: The effect of ALA was studied in vitro by determining the viability of human embryonic kidney cells (HEK293) in normoxic and hypoxic conditions as well as in vivo in two groups of chronic kidney disease (CKD) patients: non-dialyzed (ND) and undergoing continuous ambulatory peritoneal dialysis (PD) after 30 days of ALA supplementation. Results: The results revealed that the viability of HEK293 cells was significantly decreased by hypoxic conditions, while ALA administered during hypoxia increased the viability to the level observed in normoxic conditions. Studies performed in plasma of CKD patients after ALA supplementation suggested that ALA did not affect the parameters of oxidative stress, while significantly increased the level of reactive sulfane sulfur in both ND and PD patients suffering from CKD. The results suggest that ALA can exert nephroprotective effects which are related to sulfane sulfur production.

Introduction: Despite increased awareness of malnutrition and improved nutrition-related policies, there are still cases of deterioration of nutritional status during hospitalisation. NutritionDay is an audit organised by the European Society for Clinical Nutrition and Metabolism (ESPEN), the Medical University of Vienna and the Friedrich-Alexander University Erlangen-Nürnberg (FAU) to prevent the onset of malnutrition and to improve hospital policies to deal with this problem. The aim of the study was to analyse the results of the audit with regard to factors that may contribute to the deterioration of a patients’ nutritional status in hospital setting. Materials and Methods: This cross-sectional study was performed in a tertiary teaching hospital and was part of an international audit. The questionnaires used were provided by the nutritionDay office, and included information on weight loss, patients’ appetite, dietary restrictions, food intake and reasons for food rejection during hospital stay. Results: Of the examined patients, 61% reported weight loss prior to the current hospital stay. We identified 25 patients who did not consume a whole portion of their main meal on the day the audit took place. Approximately 17% of the patients’ complaints could be resolved within a hospital ward. Conclusions: Hospital patients often eat less than a standard meal portion. Identifying the reasons for meal rejection may be helpful for development of standards for nutritional care in the hospitals.

Objective: Analyze the influence of oral hygiene guidance for the maintenance of fixed partial dentures (FPD) and the influence of this treatment on the quality of life (QL) of rehabilitated patients. Material and Methods: The Simplified Oral Hygiene Index (OHI-S) and Bleeding on Probing Index (BOP) methods was employed to evaluate oral hygiene (OH), and the OHIP-14 questionnaire to assessment QL. The sample consisted of 33 patients (26 females and 7 males, mean age 51.53 years) in treatment with FPD. The OH and QL assessments were conducted in temporary FPD placing session and 30 days after definitive cementation. Results: OHI-S and BOP showed increasing results (p <0.05) comparing initial and final assessments. There was a negative correlation between OHI-S and BOP, in both periods of analysis. The OHIP-14 showed a significant result according to the Likert scale scores, with an impact reduction from 9.33 to 0.57. Conclusions: It was concluded that FPD rehabilitations need of properly oral hygiene guidance, that could be influence on oral health status. In addition, the FPD rehabilitation improved the QL of the patients.

Xanthogranulomatous Pyelonephritis (XGP) is a serious and rare inflammatory disease of unknown etiology. This systematic review analyzes XGP cases. We performed a literature search for “Pyelonephritis, Xanthogranulomatous.” The primary composite outcome was recovery with post-surgery complications, partial recovery, death, or chronic kidney disease. The secondary outcome was any presentation or treatment complication. Predictor variables consisted of demographics, history, symptoms, and diagnosis/management. Among the 251 patients, the mean age was 36.1 years, and 57.4% were female. The most common symptom and finding were fever (55.0%) and renal stones (53.8%), respectively. There were 15.5% with the composite outcome. There were 51.0% with any presentation or treatment complication. Multivariate logistic regression analysis for the composite outcome showed that kidney of both/horseshoe (OR:3.86, 95% CI:1.01, 14.73, p = 0.048), dialysis required (OR:8.64, 95% CI:2.27, 32.94, p = 0.002), and operative treatment of nephrostomy or nephrostomy followed by nephrectomy (OR:4.57, 95% CI:1.58, 13.17, p = 0.01) were each significantly associated with increased odds. Fever (OR:3.04, 95% CI:1.63, 5.67, p <0.001) and renal stones (OR:2.55, 95% CI:1.35, 4.81, p = 0.004) were each significantly associated with increased odds for any presentation/treatment complication. In conclusion, XGP patients with involvement of both or horseshoe kidneys, dialysis requirements, or treatment of nephrostomy or nephrostomy followed by nephrectomy may require aggressive treatment to mitigate poor patient outcomes.

In 2019, three regulations of the Minister of Health regarding sports medicine examinations in children, adolescents and young athletes came into force. The publication presents in detail the current scope of tests and the frequency of required medical examinations necessary to obtain medical certificates qualifying patients to practice sports. The publication also presents the Regulation of the Minister of Health on the required qualifications of doctors authorized to issue medical certificates to athletes. It is very important to properly assess the health of potential and current athletes to ensure their safety while participating in sports competitions. There are diseases that increase the risk of sudden cardiac death which doctors should keep in mind when qualifying athletes for competition. The publication draws attention to the underestimated role of echocardiography and electrocardiographic stress testing.

Background: Polycystic ovary syndrome (PCOS) is a common chronic endocrine disorder in women with complex and poorly understood etiologies. The present study aimed to describe the clinical features of PCOS in a sample of Syrian women as well as the risk factors, associated comorbid diseases, and patterns and efficacy of treatment. Methods: The present study is cross-sectional observational study conducted on a sample of Syrian women diagnosed with PCOS, using self-administered questionnaire during the period between December 25, 2023 and January 18, 2024. Overall, 1666 women with PCOS were recruited through online platforms. Results: Higher frequency of PCOS was observed in young women aged 15–25 years (63.1%) and in single ladies (76.5%). The main chief complaints experienced by patients with PCOS were hirsutism (71.25%), irregular menstrual cycle (70.95%), depressed mood (53.9%), acne (49.52%), abdominal obesity (43.88%), alopecia (38.12%), and weight gain (34.57%). The most common risk factors observed in patients with PCOS were lack of physical exercise (76.4%), unhealthy food habits (51.6%), family history (38.5%), and history of taking anabolic steroids (17.2%). Comorbid diseases were found in 11.5% of PCOS patients. These diseases were hypothyroidism (5.7%), hypertension (3.06%), dyslipidemia (1.68%), heart diseases (1.56%), and diabetes mellitus (0.78%). Most patients were treated with oral contraceptive pills (82.11%) or metformin (64.83%). The efficacy of treatment was observed as complete cure in 430 patients (25.8%) and partial response alleviating symptoms in 819 patients (49.2%), while and no benefit was found in 417 patients (25%). Conclusions: PCOS is associated with widespread dermatological and metabolic aberrations that pose psychological burden on women and increase their risk for having comorbid diseases. Most patients with PCOS do not receive adequate therapy. Understanding the risk factors and clinical features for each patient is essential to choose the proper treatment.

Background: One of the promising methods of influencing the wound process is photobiomodulation (PBM) therapy. The optimal parameters of PBM therapy have not yet been found because the molecular mechanisms of light interaction with tissue are not fully understood. Objective: Studying the influence of PBM of various parameters on the regulation of reparative processes of chronic wounds using the example of indicators of aggregation activity of platelets, platelet-derived growth factor (PDGF), interleukin-8 (IL-8), and amino-terminal propeptide of type III procollagen (PIIINP) at the remodeling stage. And also the study of the structural and functional features of chronic wound healing in an experiment under various parameters of PBM therapy. Methods: Experiments were carried out on Wistar rats. Chronic wounds were simulated. Experimental animals were exposed to PBM at a wavelength of 660 nm and an energy density of 1 J/cm2. In serum, PDGF, IL-8, and PIIINP levels were measured by enzyme-linked immunosorbent assay. The functional activity of platelets was measured using the turbidimetric method. Histological analysis was performed. Results: The work noted the dose-dependent effect of PBM using the example of platelet aggregation at the remodeling stage during the healing of chronic wounds. The use of PBM therapy resulted in increased serum PDGF levels. Histological examination data indicate a positive effect of PBM therapy on the wound healing process. Conclusions: The effectiveness of the use of PBM therapy for the healing of chronic wounds to regulate reparative processes has been proven.

The text is dedicated to the outstanding Polish researcher of proper names — prof. Aleksandra Cieślikowa, author and co-author of many significant monographs and onomasticons, which went beyond the limits of previous onomastic studies. The most important, selected her scientific achievements and expert activities at the Polish Language Council and the Commission on Names of Localities and Physiographic Objects were presented.

The article presents the achievements of professor Aleksandra Cieślikowa in the field of word-formation of proper names. The most important issues concerning the creation of anthroponyms in the Old Polish era selected from monographs and scientific articles are detailed. These issues include the problems of motivation in onomastic word-formation, the onimization process and the way of describing non-derivatized words by word formation and the participation of paradigmatic derivation in the emergence of Old Polish personal names. The views of Aleksandra Cieślikowa regarding Old Polish anthroponymy contributed to the development of onomastic word-formation, an integral part of the grammar of proper names and gave methodological foundations for the description of Old Polish personal names from a synchronic perspective.

The text, inspired by the book in question, is devoted to contemporary investigations of Slovak terrain names, presenting them to the Polish reader. The main questions discussed are perspectives of a study of the archaic lexical stock, chiefly of Slavic origin, conserved in Slovak toponymy, as well as the current organization of the dictionary entry, which is judged to be far from optimal. Some corrections to the entries in A- regarding concrete etymological solutions are suggested as well.

The aim of the article is to present the attestations of contemporary Polish surnames of Lithuanian origin which are absent from the dictionary of Lithuanian surnames (“Lietuvių pavardžių žodynas”, LPŽ), excerpted from the anthroponymic index card files that have been stored in the Lithuanian Language Institute in Vilnius and continually enlarged for several decades now. The files contain data excerpted from historical sources of the 16th to 19th centuries and consist of about 200,000 index cards (the actual number of excerpted anthroponyms is lower since some recur in various sources). Due to space limitations, generally only directly attested names have been included in the article, to the exclusion of those whose relationship with the researched name can be inferred rather than considered proven. Each listed attestation of an anthroponym (probably not in all cases an already established hereditary surname) is accompanied by information concerning its location and year (or time bracket), wherever available in the card index file. Given names or other details (e.g. the role of the person mentioned in documents, such as godmother in the data excerpted from baptismal registers) have only been included occasionally, if there was some reason to do so.

The onymic image of the world in a translation through an intermediary language as exemplified by the anthroponyms in a collection of short stories “Baummoos pflücken” (lit. “The Lichen Collector”) by Zhang Wei.

The article addresses the issue of the linguistic image of the world — reflected in proper names — and of its translation. Chinese onyms and their related forms of address contain information about mutual relations between the speaker and the named object, thus offering a better insight into social relations in small language and cultural communities. The challenge for the translator is not only to translate these onyms, but also to preserve their social function in the text. This has been exemplified in the article by a translation of a collection of short stories from Chinese to Polish through German, where the intermediary language adds another coherence layer. The theory of the linguistic image of the world and proper names per se are a starting point for a critical analysis of this specific translation in view of the translation of onyms and of their potential for conveying the image of the world. Emphasis is placed on the transfer of the social functions of onyms into the target language. The influence of onyms and of their consistent treatment in the translation on the coherence of the studied text has also been taken into account.

The names of stations in the Way of the Cross may be used as titles of pictures and sculptures, each corresponding to a particular event in the Passion of Christ, or as titles of meditations. The article focuses on the second meaning, but the trends of the development of both kinds of names are similar. The study is based on material consisting of about 200 texts of the service that have been published from the beginning of the 20th century to the present (2020). The purpose of the article is to describe the changes that have taken place in the 20th century, a period of particularly turbulent changes in religious discourse. The article deals with the function, syntactic structure and features of style, such as the use of archaic or colloquial vocabulary. These properties are considered in connection with social and cultural changes. At the beginning of the analyzed period, it was customary to use relatively long titles, which informed the participant or reader about a particular event using expressive and evaluative lexis. Those titles gradually gave way to short, schematic names. Since the Second Vatican Council, titles of a new type have appeared. Their purpose is to attract the attention of the recipient. They are based on a riddle, a contrast, allusions, etc. Therefore, the recipient derives satisfaction from deciphering the puzzle or finding the source of the quote or allusion. These phenomena are known from research on the language of press or fiction, but they can also be linked to current trends in the so-called new evangelization.

This article examines the localness of commercial names in Finland and focusses specifically on the names of grill food kiosks and products. There are two research objectives: firstly, to determine the number of local names that occur in the material, and secondly, to analyse how these names work as indexes of localness. This article explores the claim by sociolinguist Barbara Johnstone that particular linguistic forms can index meanings along a variety of dimensions and some forms may index locality. Furthermore, these types of linguistic forms can be used in discourses that shape people’s senses of place and the social identities associated with place. Of the 15 names of kiosks, almost all names, a total of 13 names, can be interpreted as manifesting local characteristics. Most of the kiosk names include a local place name. Of the product names, more than half (46 out of 84 names) are to be construed as describing something local. Although most of the local names in the group of product names include a local place name, personal names are also rather common. In addition, local dialect or slang is also visible in the product names. Another type of reference to a region appears in two kiosk names and in some of the product names. These names constitute a special case and demonstrate how local history can be incorporated in names creatively.