@ARTICLE{Budnik_Monika_Serum_2020,
 author={Budnik, Monika and Białek, Sławomir and Peller, Michał and Kiszkurno, Agata and Kochanowski, Janusz and Kucharz, Jakub and Sitkiewicz, Dariusz and Opolski, Grzegorz},
 volume={Vol. 60},
 number={No 1},
 journal={Folia Medica Cracoviensia},
 pages={5-13},
 howpublished={online},
 year={2020},
 publisher={Oddział PAN w Krakowie; Uniwersytet Jagielloński – Collegium Medicum},
 abstract={B a c k g r o u n d: Today no established biomarkers are available for the early diagnosis of takotsubo syndrome and its differentiation from ST-segment elevation myocardial infarction. We hypothesized that copeptin and copeptin/NT-proBNP ratio may serve a routine marker combination for non-invasive differentiation. M e t h o d s: The study compared the serum concentrations of copeptin, troponin I (TnI) and NT-proBNP in 19 consecutive women diagnosed with takotsubo syndrome according to the Mayo Clinic criteria and 10 consecutive women diagnosed with ST-segment elevation myocardial infarction. R e s u l t s: Copeptin concentrations were significantly lower in patients with takotsubo syndrome than in patients with ST-segment elevation myocardial infarction. The diagnostic accuracy to distinguish takotsubo syndrome from ST-segment elevation myocardial infarction is highest for copeptin/NTproBNP ratio, copeptin/TnI at admission ratio and copeptin alone (AUC 0.8713, 0.8538, 0.8480, respectively). C o n c l u s i o n s: The serum copeptin to NTproBNP ratio could be an additional tool in the non-invasive differentiation between takotsubo syndrome and ST-segment elevation myocardial infarction. However, further researches are needed.},
 type={Article},
 title={Serum copeptin and copeptin/NT-proBNP ratio — new tools to differentiate takotsubo syndrome from acute myocardial infarction},
 URL={http://journals.pan.pl/Content/116628/PDF/2020-01-FOMC-01-Budnik-etal.pdf},
 doi={10.24425/fmc.2020.133481},
 keywords={copeptin, takotsubo syndrome, acute myocardial infarction},
}