@ARTICLE{Csapai_A._Study_2022, author={Csapai, A. and Țoc, D.-A. and Pașcalău, V. and Toșa, V. and Opruța, D. and Popa, F. and Popa, C.}, volume={vol. 67}, number={No 3}, journal={Archives of Metallurgy and Materials}, pages={1071-1078}, howpublished={online}, year={2022}, publisher={Institute of Metallurgy and Materials Science of Polish Academy of Sciences}, publisher={Committee of Materials Engineering and Metallurgy of Polish Academy of Sciences}, abstract={This paper presents a comparative study on the effects of the in-situ surface modifications performed on “H” type microfluidic systems obtained via additive manufacturing. The microsystem was printed using a polylactic acid filament on an Ender-5 Pro printer. The surface modification of the main channel was done using chloroform by two different methods: vapor smoothing and flushing. The obtained surface roughness was studied using an optical microscope and the ImageJ software, as well as scanning electron microscopy. The effect of the channel surface treatment upon the characteristics of the fluid flow was assessed. The microfluidic systems were used for the dynamic study of biofilm growth of Candida albicans (ATCC 10231). The influence of the surface roughness of the main channel on the formation and growth of the biofilm was studied using quantitative methods, scanning electron microscopy imaging as well as optical coherence tomography.}, type={Article}, title={Study on the Effect of in Situ Surface Treatments of Medical Microfluidic Systems Obtained Through Additive Manufacturing}, URL={http://journals.pan.pl/Content/124061/PDF-MASTER/AMM-2022-3-36-Csapai.pdf}, doi={10.24425/amm.2022.139705}, keywords={additive manufacturing, microfluidic systems, surface roughness, biofilm growth, laminar flow}, }