@ARTICLE{Iksat_Nurgul_Plant_2023,
 author={Iksat, Nurgul and Masalimov, Zhaksylyk and Omarov, Rustem},
 number={No 57},
 pages={147-158},
 journal={Journal of Water and Land Development},
 howpublished={online},
 year={2023},
 publisher={Polish Academy of Sciences; Institute of Technology and Life Sciences - National Research Institute},
 abstract={Plant viruses cause crop losses in agronomically and economically important crops, making global food security a challenge. Although traditional plant breeding has been effective in controlling plant viral diseases, it is unlikely to solve the problems associated with the frequent emergence of new and more virulent virus species or strains. As a result, there is an urgent need to develop alternative virus control strategies that can be used to more easily contain viral diseases. A better understanding of plant defence mechanisms will open up new avenues for research into plant- pathogen interactions and the development of broad-spectrum virus resistance. The scientific literature was evaluated and structured in this review, and the results of the reliability of the methods of analysis used were filtered. As a result, we described the molecular mechanisms by which viruses interact with host plant cells. To develop an effective strategy for the control of plant pathogens with a significant intensity on the agricultural market, clear and standardised recommendations are required. The current review will provide key insights into the molecular underpinnings underlying the coordination of plant disease resistance, such as main classes of resistance genes, RNA interference, and the RNA-mediated adaptive immune system of bacteria and archaea – clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated Cas proteins – CRISPR/Cas. Future issues related to resistance to plant viral diseases will largely depend on integrated research to transfer fundamental knowledge to applied problems, bridging the gap between laboratory and field work.},
 type={Article},
 title={Plant virus resistance biotechnological approaches: From genes to the CRISPR/Cas gene editing system},
 URL={http://journals.pan.pl/Content/127430/PDF/2023-02-JWLD-16.pdf},
 doi={10.24425/jwld.2023.145345},
 keywords={CRISPR/Cas9, CRISPR/Cas13, plant disease resistance, plant immunity, plant viruses},
}