TY - JOUR N2 - Malakoplakia is regarded as a chronic granulomatous infl ammatory disease with a good prognosis. It usually aff ects the urinary system, especially the urinary bladder. Bacterial infections, including E. coli are thought to be the main factor in pathogenesis. It frequently coexists with chronic diseases and immunosuppression state. Histopathological examination of aff ected tissue samples is thought to be the best diagnostic method. Th e basic microscopic feature is mixed infl ammatory infi ltration containing foamy histiocytes known as von Hansemann cells, frequently with basophilic inclusions known as Michaelis-Gutmann bodies. Symptoms and the clinical course of malakoplakia depend on location and the extent of the lesions. Th e lesion is treated successfully with antibiotic therapy and surgical excision. L1 - http://journals.pan.pl/Content/112059/PDF/FMC%202-19%207-Cieszczyk.pdf L2 - http://journals.pan.pl/Content/112059 PY - 2019 IS - No 2 EP - 74 DO - 10.24425/fmc.2019.128455 KW - malakoplakia KW - von Hansemann cells KW - Michaelis-Gutmann bodies A1 - Cięszczyk, Katarzyna A1 - Puderecki, Michał A1 - Wronecki, Lech A1 - Burdan, Franciszek A1 - Szumiło, Justyna PB - Oddział PAN w Krakowie; Uniwersytet Jagielloński – Collegium Medicum VL - vol. 59 DA - 2019.10.23 T1 - Malakoplakia of the urinary system SP - 67 UR - http://journals.pan.pl/dlibra/publication/edition/112059 T2 - Folia Medica Cracoviensia ER -