TY - JOUR N2 - Polyvinylidene fluoride (PVDF) is one of the most important piezoelectric polymers. Piezoelectricity in PVDF appears in polar b and ɣ phases. Piezoelectric fibers obtained by means of electrospinning may be used in tissue engineering (TE) as a smart analogue of the natural extracellular matrix (ECM). We present results showing the effect of rotational speed of the collecting drum on morphology, phase content and in vitro biological properties of PVDF nonwovens. Morphology and phase composition were analyzed using scanning electron microscopy (SEM) and Fourier-transform infrared spectroscopy (FTIR), respectively. It was shown that increasing rotational speed of the collector leads to an increase in fiber orientation, reduction in fiber diameter and considerable increase of polar phase content, both b and g. In vitro cell culture experiments, carried out with the use of ultrasounds in order to generate electrical potential via piezoelectricity, indicate a positive effect of polar phases on fibroblasts. Our preliminary results demonstrate that piezoelectric PVDF scaffolds are promising materials for tissue engineering applications, particularly for neural tissue regeneration, where the electric potential is crucial. L1 - http://journals.pan.pl/Content/116524/PDF/24_627-633_01433_Bpast.No.68-3_30.06.20_K1A.pdf L2 - http://journals.pan.pl/Content/116524 PY - 2020 IS - No. 3 EP - 633 DO - 10.24425/bpasts.2020.133368 KW - scaffolds KW - electrospinning KW - polyvinylidene fluoride KW - tissue engineering A1 - Zaszczyńska, A. A1 - Sajkiewicz, P.Ł. A1 - Gradys, A. A1 - Tymkiewicz, R. A1 - Urbanek, O. A1 - Kołbuk, D. VL - 68 DA - 30.06.2020 T1 - Influence of process-material conditions on the structure and biological properties of electrospun polyvinylidene fluoride fibers SP - 627 UR - http://journals.pan.pl/dlibra/publication/edition/116524 T2 - Bulletin of the Polish Academy of Sciences Technical Sciences ER -