TY - JOUR N2 - Maternal-fetal medicine is a dynamically developing field, which enables not only to diagnose and treat maternal diseases but also condtions of an unoborn child developing in a womb. Fetal therapy is a highly specialized branch of maternal-fetal medicine which offers surgeries before birth. Prenatal intervensions aim to correct or diminish unfavorable effects of a fetal congenital defect. However, the starting point for a succesful intrauterine therapy is always a thorough prenatal diagnosis and an extensive knowledge regarding fetal pathophysiology in each case. Fetal surgery is now an established but still rapidly evolving specialty, born from the rationale that destructive embryologic processes, recognized early in gestation, can be curtailed by prenatal correction. Prenatal surgical techniques have evolved from highly invasive interventions involving hysterotomy to minimally- invasive fetoscopic interventions. However, there is still space for research aiming to find solutions including pharmacological treatment. In this review we aimed to present various conditions in which fetal surgery has been attempted and the present the current status of this specialty. L1 - http://journals.pan.pl/Content/124606/PDF-MASTER/N%23322-05-Wielgo%C5%9B.pdf L2 - http://journals.pan.pl/Content/124606 PY - 2022 IS - No 3 EP - 90 DO - 10.24425/nauka.2022.140346 KW - fetal therapy KW - fetal surgery KW - prenatal therapy A1 - Wielgoś, Mirosław A1 - Dębska, Marzena A1 - Lipa, Michał A1 - Litwińska, Ewelina A1 - Litwińska, Magdalena A1 - Mazanowska, Natalia PB - Biuro Upowszechniania i Promocji Nauki PAN DA - 2022.10.04 T1 - Fetal therapy SP - 53 UR - http://journals.pan.pl/dlibra/publication/edition/124606 T2 - Nauka ER -