Relevance of Molecular Changes in the ND4 Gene in German Shepherd Dog Tumours

Journal title

Polish Journal of Veterinary Sciences




No 3


Divisions of PAS

Nauki Biologiczne i Rolnicze


Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn




DOI: 10.1515/pjvs-2016-0058 ; ISSN 1505-1773


Polish Journal of Veterinary Sciences; 2016; No 3


Surdyka (2016), Defect in ND and COX mitochondrial genes as a risk factor for canine mammary tumour, Vet Comp Oncol, ; Slaska (2011), Analysis of the mitochondrial haplogroups of farm and wild - living raccoon dogs in Poland, Mitochondrial DNA, 22, 105, ; Brandon (2006), Mitochondrial mutations in cancer, Oncogene, 25, 4647, ; Slaska (2014), Mitochondrial D - loop mutations and polymorphisms are connected with canine malignant cancers, Mitochondrial DNA, 25, 238, ; Parmley (2007), How do synonymous mutations affect fitness, Bioessays, 29, 515, ; Jasik (2009), Epidemiological analysis of canine skin tumors, Med Weter, 65, 848. ; Grzybowska (2014), Mitochondrial NADH dehydrogenase polymorphisms are associated with breast cancer in Poland, J Appl Genet, 55, 173, ; Murgia (2006), Clonal Origin and Evolution of a Transmissible Cancer, Cell, 126. ; Ślaska (2014), Mitochondrial D - loop mutations can be detected in sporadic malignant tumours in dogs, Bull Vet Inst Pulawy, 58, 631, ; Grzybowska (2012), a Mitochondrial DNA and carcinogenesis, review Mol Med Rep, 6, 923. ; Grzybowska (2014), Novel mitochondrial mutations in the ATP and ATP genes in patients with breast cancer, Mol Med Rep, 8, 1772. ; Treggiari (2015), A descriptive review of cardiac tumours in dogs and cats, Vet Comp Oncol, ; Jónasdóttir (2000), Genetic mapping of a naturally occurring hereditary renal cancer syndrome in dogs, Proc Natl Acad Sci USA, 97, 4132, ; Mendoza (1997), Status of the p and MDM genes in canine osteosarcoma, Anticancer Res, 18, 4449. ; Abu (2005), High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines, Oncogene, 24, 1455, ; Kaldrymidou (2002), Prevalence , Distribution and Factors Associated with the Presence and the Potential for Malignancy of Cutaneous Neoplasms in Dogs Admitted to a Clinic in Northern Greece, J Vet Med A, 49. ; Kim (1998), The complete nucleotide sequence of the domestic dog ( Canis familiaris ) mitochondrial genome, Mol Phylogenet Evol, 10, 210, ; Surdyka (2016), a Defect of the mitochondrial DNA hypervariable region as a risk factor for canine mammary tumour, Vet Comp Oncol, ; Grzybowska (2012), Polymorphisms in genes encoding mt - tRNA in female breast cancer in Poland, Mitochondrial DNA, 23, 106, ; Amero (2006), Mitochondrial abnormalities in patients with LHON - like optic neuropathies, Invest Ophthalmol Vis Sci, 47, 4211, ; Parrella (2001), Detection of mitochondrial DNA mutations in primary breast cancer and fine - needle aspirates, Cancer Res, 61, 7623. ; Nackley (2006), Human catechol - O - methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure, Science, 314. ; Dobson (2013), Breed - Predispositions to Cancer in Pedigree Dogs, ISRN Vet Sci, 941275. ; Peterson (2000), A Study of the Lifetime Occurrence of Neoplasia and Breed Differences in a Cohort of German Shepherd Dogs and Belgian Malinois Military Working Dogs that Died in, J Vet Intern Med, 14, 140, ; Davis (2014), Domestic dogs and cancer research : a breed - based genomics approach, ILAR J, 55. ; Lu (2009), Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis, Cell Res, 19, 802, ; Slaska (2015), Mitochondrial DNA polymorphism in genes encoding ND COI and CYTB in canine malignant cancers, Mitochondrial DNA, 26, 452, ; Bertagnolli (2009), An assessment of the clonality of the components of canine mixed mammary tumors by mitochondrial DNA analysis, Vet J, 182. ; Salas (2015), Epidemiological Study of Mammary Tumors in Female Dogs Diagnosed during the Period Growing Animal Health Problem, PLoS One, 10. ; Bianchi (2001), Mitochondrial genome instability in human cancers, Mutat Res, 488. ; Ślaska (2013), Nuclear and mitochondrial DNA mutation in human and canine tumors, Med Weter, 69, 195.