Albasha MO, Azab AE (2016) Hepatorenal Protective Effects of Pomegranate (Punica granatum) Juice against Nicotine Induced Toxicity in Guinea Pigs. J Adv Biol Biotechnol 5: 1-13.

Ateyya H, Nader MA, Attia GM, El-Sherbeeny NA (2017) Influence of alpha-lipoic acid on nicotine-induced lung and liver damage in experimental rats. Can J Physiol Pharmacol 95: 492-500.

Azab AE, Albasha MO (2015) Simultaneous Administration of Aqueous Extract of Rosmarinus officinal with Nicotine Resulted in Prevention of Induced Hepatorenal Toxicity in Guinea Pigs. Amer J Biosci Bioeng 3: 80-86.

Bandyopadhyaya G, Sinha S, Chattopadhyay BD, Chakraborty A (2008) Protective role of curcumin against nicotine-induced genotoxicity on rat liver under restricted dietary protein. Eur J Pharmacol 588: 151-157.

Carpentieri A, Díaz de Barboza G, Areco V, Peralta López M, Tolosa de Talamoni N (2012) New perspectives in melatonin uses. Pharmacol Res 65: 437-444.

Chattopadhyay K, Mondal S, Chattopadhyay B, Ghosh S (2010) Ameliorative effect of sesame lignans on nicotine toxicity in rats. Food Chem Toxicol 48: 3215-3220.

Dailah HG (2022) Potential of Therapeutic Small Molecules in Apoptosis Regulation in the Treatment of Neurodegenerative Diseases: An Updated Review. Molecules 27: 7207.

Dasgupta P, Kinkade R, Joshi B, DeCook C, Haura E, Chellappan S (2006) Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin. Proc Natl Acad Sci USA 103: 6332-6337.

Dey S, Nandi A, Das S, Sinha SK, Dey SK (2023) Nicotine and Chromium Co-exposure Lead to Hepatotoxicity in Male Albino Rats. J Stress Physiol Biochem 19: 24-34.

Durgun C, Aşır F (2023) Daidzein alleviated the pathologies in intestinal tissue against ischemia-reperfusion. Eur Rev Med Pharmacol Sci 27: 1487-1493.

El-Sherbeeny NA, Nader MA, Attia GM, Ateyya H (2016) Agmatine protects rat liver from nicotine-induced hepatic damage via antioxidative, antiapoptotic, and antifibrotic pathways. Naunyn Schmiedebergs Arch Pharmacol 389: 1341-1351.

El-Sokkary GH, Cuzzocrea S, Reiter RJ (2007) Effect of chronic nicotine administration on the rat lung and liver: beneficial role of melatonin. Toxicology 239: 60-67.

Heusch WL, Maneckjee R (1998) Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. Carcinogenesis 19: 551-556.

Ivey R, Desai M, Green K, Sinha-Hikim I, Friedman TC, Sinha-Hikim AP (2014) Additive Effects of Nicotine and High-Fat Diet on Hepatocellular Apoptosis in Mice: Involvement of Caspase 2 and Inducible Nitric Oxide Synthase-Mediated Intrinsic Pathway Signaling Horm Metab Res 46: 568-573.

Jalili C, Salahshoor MR, Moradi MT, Ahookhash M, Taghadosi M, Sohrabi M (2017) Expression Changes of Apoptotic Genes in Tissues from Mice Exposed to Nicotine. Asian Pac J Cancer Prev 18: 239-244.

Kang SW, Park HJ, Ban JY, Chung JH, Chun GS, Cho JO (2011) Effects of nicotine on apoptosis in human gingival fibroblasts. Arch Oral Biol 56: 1091-1097.

Khalaf HA, Ghoneim FM, Arafat EA, Mahmoud EHM (2017) Histological effect of nicotine on adrenal zona fasciculata and the effect of grape seed extract with or without withdrawal of nicotine. J Microsc Ultrastruct 5: 123-131.

Kim HJ, Park KK, Chung WY, Lee SK, Kim KR (2017) Protective Effect of White-fleshed Peach (Prunus persica (L.) Batsch) on Chronic Nicotine-induced Toxicity. J Cancer Prev 22: 22-32.

Kurus M, Esrefoglu M, Sogutlu G, Atasever A (2009) Melatonin Prevents Cyclosporine-Induced Hepatotoxicity in Rats. Med Princ Pract 18: 407-410.

Liang YL, Zhang ZH, Liu XJ, Liu XQ, Tao L, Zhang YF, Wang H, Zhang C, Chen X, Xu DX (2012) Melatonin Protects against Apoptosis-Inducing Factor (AIF)-Dependent Cell Death during Acetaminophen-Induced Acute Liver Failure. PLoS One 7: e51911.

Mahmoud GS, Amer AS (2014) Protective Effects of Vitamin C against Nicotine-Induced Oxidative Damage of Rat Liver and Kidney. IOSR J Environ Sci Toxicol Food Technol 8: 50-63.

Mercan S, Eren B (2012) Protective role of melatonin supplementation against nicotine-induced liver damage in mouse. Toxicol Ind Health 29: 888-896.

Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death. Cell 74: 609-619.

Othman MS, Fareid MA, Abdel Hameed RS, Abdel Moneim AE (2020) The Protective Effects of Melatonin on Aluminum-Induced Hepatotoxicity and Nephrotoxicity in Rats. Oxid Med Cell Longev 2020: 7375136.

Oztopuz O, Turkon H, Buyuk B, Coskun O, Sehitoglu MH, Ovali MA, Uzun M (2020) Melatonin ameliorates sodium valproate‑induced hepatotoxicity in rats. Mol Biol Rep 47: 317-325.

Saad AB, Rjeibi I, Brahmi N, Elaloui E, Zouari N (2020) Nicotine‑induced oxidative stress, testis injury, AChE inhibition and brain damage alleviated by Mentha spicata. Inflammopharmacology 28: 939-948.

Sainz RM, Mayo JC, Rodriguez C, Tan DX, Lopez-Burillo S, Reiter RJ (2003) Melatonin and cell death: differential actions on apoptosis in normal and cancer cells. Cell Mol Life Sci 60: 1407-1426.

Strasser A, O’Connor L, Dixit VM (2000) Apoptosis signaling. Annu Rev Biochem 69: 217-245.

Tuñón MJ, San Miguel B, Crespo I, Jorquera F, Santamaría E, Alvarez M, Prieto J, González-Gallego J (2010) Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus. J Pineal Res 50: 38-45.

Williams GT (1991) Programmed Cell Death: Apoptosis and Oncogenesis. Cell 65: 1097-1098.

Yang Z, He Y, Wang H, Zhang Q (2021) Protective effect of melatonin against chronic cadmium-induced hepatotoxicity by suppressing oxidative stress, inflammation, and apoptosis in mice. Ecotoxicol Environ Saf 228: 112947.

Zeng F, Li YC, Chen G, Zhang YK, Wang YK, Zhou SQ, Ma LN, Zhou JH, Huang YY, Zhu WY, Liu XG (2012) Nicotine inhibits cisplatin-induced apoptosis in NCI-H446 cells. Med Oncol 29: 364-373.

Zhang JJ, Meng X, Li Y, Zhou Y, Xu DP, Li S, Li HB (2017) Effects of Melatonin on Liver Injuries and Diseases. Int J Mol Sci 18: 673.