Details
Title
Genetic variation and recombination analysis of the NSP11 gene of Porcine reproductive and respiratory syndrome-2 strains in China from 1996 to 2022Journal title
Polish Journal of Veterinary SciencesYearbook
2025Volume
vol. 28Issue
No 1Authors
Affiliation
Zheng, Y. : Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, 528225, China ; Li, G. : Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, 528225, China ; Sun, R. : Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, 528225, China ; Luo, Q. : Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, 528225, China ; Zhao, M. : Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, 528225, ChinaKeywords
Porcine reproductive and respiratory syndrome virus ; non-structural protein 11 ; genetic variation ; recombinationDivisions of PAS
Nauki Biologiczne i RolniczeCoverage
5–16Publisher
Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in OlsztynBibliography
Chand RJ, Trible BR, and Rowland RR (2012) Pathogenesis of porcine reproductive and respiratory syndrome virus. Curr Opin Virol 2: 256-263.
Contreras-Luna MJ, Fragoso-Gonzalez G, Segura-Velázquez RA, Cervantes-Torres JB, Alonso-Morales R, Ramírez-Martínez LA, Ayón-Núñez DA, Bobes RJ, and Sánchez-Betancourt JI (2022) Immunogenic and antigenic analysis of recombinant NSP1 and NSP11 of PRRS virus. Vet Med Sci 8: 610-618.
Darwich L, Gimeno M, Sibila M, Diaz I, de la Torre E, Dotti S, Kuzemtseva L, Martin M, Pujols J, and Mateu E (2011) Genetic and immunobiological diversities of porcine reproductive and respiratory syndrome genotype I strains. Vet Microbiol 150: 49-62.
Dong H, Zhou L, Ge X, Guo X, Han J, and Yang H (2018) Porcine reproductive and respiratory syndrome virus nsp1β and nsp11 antagonize the antiviral activity of cholesterol-25-hydroxylase via lysosomal degradation. Vet Microbiol 223: 134-143.
Dwivedi V, Manickam C, Binjawadagi B, Linhares D, Murtaugh MP, and Renukaradhya GJ (2012) Evaluation of immune responses to porcine reproductive and respiratory syndrome virus in pigs during early stage of infection under farm conditions. Virol J 9: 45.
Guo Z, Chen XX, Li R, Qiao S, and Zhang G (2018) The prevalent status and genetic diversity of porcine reproductive and respiratory syndrome virus in China: a molecular epidemiological perspective. Virol J 15: 2.
Jiang Y, Li G, Yu L, Li L, Zhang Y, Zhou Y, Tong W, Liu C, Gao F, and Tong G (2020) Genetic Diversity of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) From 1996 to 2017 in China. Front Microbiol 11: 618.
Kappes MA, and Faaberg KS (2015) PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity. Virology 479-480: 475-486.
Kuhn JH, Lauck M, Bailey AL, Shchetinin AM, Vishnevskaya TV, Bào Y, Ng TF, LeBreton M, Schneider BS, Gillis A, Tamoufe U, Diffo Jle D, Takuo JM, Kondov NO, Coffey LL, Wolfe ND, Delwart E, Clawson AN, Postnikova E, Bollinger L, Lackemeyer MG, Radoshitzky SR, Palacios G, Wada J, Shevtsova ZV, Jahrling PB, Lapin BA, Deriabin PG, Dunowska M, Alkhovsky SV, Rogers J, Friedrich TC, O’Connor DH, and Goldberg TL (2016) Reorganization and expansion of the nidoviral family Arteriviridae. Arch Virol 161: 755-768.
Li B, Fang L, Xu Z, Liu S, Gao J, Jiang Y, Chen H, and Xiao S (2009) Recombination in vaccine and circulating strains of porcine reproductive and respiratory syndrome viruses. Emerg Infect Dis 15: 2032-2035.
Li C, Zhuang J, Wang J, Han L, Sun Z, Xiao Y, Ji G, Li Y, Tan F, Li X, and Tian K (2016) Outbreak Investigation of NADC30-Like PRRSV in South-East China. Transbound Emerg Dis 63: 474-479.
Lu WH, Tun HM, Sun BL, Mo J, Zhou QF, Deng YX, Xie QM, Bi YZ, Leung FC, and Ma JY (2015) Re-emerging of porcine respiratory and reproductive syndrome virus (lineage 3) and increased pathogenicity after genomic recombination with vaccine variant. Vet Microbiol 175: 332-340.
Meng XJ, Paul PS, Halbur PG, and Lum MA (1995) Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe. Arch Virol 140: 745-755.
Meulenberg JJ, Hulst MM, de Meijer EJ, Moonen PL, den Besten A, de Kluyver EP, Wensvoort G, and Moormann RJ (1993) Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology 192: 62-72.
Montaner-Tarbes S, Del Portillo HA, Montoya M, and Fraile L (2019) Key Gaps in the Knowledge of the Porcine Respiratory Reproductive Syndrome Virus (PRRSV). Front Vet Sci 6: 38.
Nedialkova DD, Ulferts R, van den Born E, Lauber C, Gorbalenya AE, Ziebuhr J, and Snijder EJ (2009) Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease. J Virol 83: 5671-5682.
Nelsen CJ, Murtaugh MP, and Faaberg KS (1999) Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents. J Virol 73: 270-280.
Neumann EJ, Kliebenstein JB, Johnson CD, Mabry JW, Bush EJ, Seitzinger AH, Green AL, and Zimmerman JJ (2005) Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States. J Am Vet Med Assoc 227: 385-392.
Paploski IAD, Corzo C, Rovira A, Murtaugh MP, Sanhueza JM, Vilalta C, Schroeder DC, and VanderWaal K (2019) Temporal Dynamics of Co-circulating Lineages of Porcine Reproductive and Respiratory Syndrome Virus. Front Microbiol 10: 2486.
Paploski IAD, Pamornchainavakul N, Makau DN, Rovira A, Corzo CA, Schroeder DC, Cheeran MC, Doeschl-Wilson A, Kao R R, Lycett S, and VanderWaal K (2021) Phylogenetic Structure and Sequential Dominance of Sub-Lineages of PRRSV Type-2 Lineage 1 in the United States. Vaccines (Basel) 9: 608.
Sha H, Zhang H, Luo Q, Zheng Y, Zhu Q, Wang N, Qin L, Li H, Huang L, and Zhao M (2023) Variations in the NSP4 gene of the type 2 porcine reproductive and respiratory syndrome virus isolated in China from 1996 to 2021. Virus Genes 59: 109-120.
Shi M, Lam TT, Hon CC, Hui RK, Faaberg KS, Wennblom T, Murtaugh MP, Stadejek T, and Leung FC (2010a) Molecular epidemiology of PRRSV: a phylogenetic perspective. Virus Res 154: 7-17.
Shi M, Lam TT, Hon CC, Murtaugh MP, Davies PR, Hui RK, Li J, Wong LT, Yip CW, Jiang JW, and Leung FC (2010b) Phylogeny-based evolutionary, demographical, and geographical dissection of North American type 2 porcine reproductive and respiratory syndrome viruses. J Virol 84: 8700-8711.
Shi Y, Li Y, Lei Y, Ye G, Shen Z, Sun L, Luo R, Wang D, Fu ZF, Xiao S, and Peng G (2016) A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of Porcine Reproductive and Respiratory Syndrome Virus nsp11. J Virol 90: 4579-4592.
Snijder EJ, and Meulenberg JJ (1998) The molecular biology of arteriviruses. J Gen Virol 79 (Pt 5): 961-979.
Sun Y, Ke H, Han M, Chen N, Fang W, and Yoo D (2016) Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus Suppresses Both MAVS and RIG-I Expression as One of the Mechanisms to Antagonize Type I Interferon Production. PLoS One 11: e0168314.
Sun Y, Li D, Giri S, Prasanth SG, and Yoo D (2014) Differential host cell gene expression and regulation of cell cycle progression by nonstructural protein 11 of porcine reproductive and respiratory syndrome virus. Biomed Res Int 2014: 430508.
Tian K (2017) NADC30-Like Porcine Reproductive and Respiratory Syndrome in China. Open Virol J 11: 59-65.
Tian K, Yu X, Zhao T, Feng Y, Cao Z, Wang C, Hu Y, Chen X, Hu D, Tian X, Liu D, Zhang S, Deng X, Ding Y, Yang L, Zhang Y, Xiao H, Qiao M, Wang B, Hou L, Wang X, Yang X, Kang L, Sun M, Jin P, Wang S, Kitamura Y, Yan J, and Gao GF (2007) Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark. PLoS One 2: e526.
Wang H, Du L, Liu F, Wei Z, Gao L, and Feng WH (2019) Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Induces Interleukin-17 Production via Activation of the IRAK1-PI3K-p38MAPK-C/EBPβ/CREB Pathways. J Virol 93: e01100-19.
Wenhui L, Zhongyan W, Guanqun Z, Zhili L, JingYun M, Qingmei X, Baoli S, and Yingzuo B (2012) Complete genome sequence of a novel variant porcine reproductive and respiratory syndrome virus (PRRSV) strain: evidence for recombination between vaccine and wild-type PRRSV strains. J Virol 86: 9543.
Wootton S, Yoo D, and Rogan D (2000) Full-length sequence of a Canadian porcine reproductive and respiratory syndrome virus (PRRSV) isolate. Arch Virol 145: 2297-2323.
Yin B, Qi S, Sha W, Qin H, Liu L, Yun J, Zhu J, Li G, and Sun D (2021) Molecular Characterization of the Nsp2 and ORF5 (ORF5a) Genes of PRRSV Strains in Nine Provinces of China During 2016-2018. Front Vet Sci 8: 605832.
Yu F, Yan Y, Shi M, Liu HZ, Zhang HL, Yang YB, Huang XY, Gauger PC, Zhang J, Zhang YH, Tong GZ, Tian ZJ, Chen JJ, Cai XH, Liu D, Li G, and An TQ (2020) Phylogenetics, Genomic Recombination, and NSP2 Polymorphic Patterns of Porcine Reproductive and Respiratory Syndrome Virus in China and the United States in 2014-2018. J Virol 94: e01813-19.
Zhang H, Luo Q, Zheng Y, Sha H, Li G, Kong W, Huang L, and Zhao M (2023a) Genetic Variability and Recombination of the NSP2 Gene of PRRSV-2 Strains in China from 1996 to 2021. Vet Sci 10: 325.
Zhang M, Li X, Deng Z, Chen Z, Liu Y, Gao Y, Wu W, and Chen Z (2017) Structural Biology of the Arterivirus nsp11 Endoribonucleases. J Virol 91: e01309-1.
Zhao HZ, Wang FX, Han XY, Guo H, Liu CY, Hou LN, Wang YX, Zheng H, Wang L, and Wen YJ (2022) Recent advances in the study of NADC34-like porcine reproductive and respiratory syndrome virus in China. Front Microbiol 13: 950402.
Zhao K, Ye C, Chang XB, Jiang CG, Wang SJ, Cai XH, Tong GZ, Tian ZJ, Shi M, and An TQ (2015) Importation and Recombination Are Responsible for the Latest Emergence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in China. J Virol 89: 10712-10716.
Zhou L, Wang Z, Ding Y, Ge X, Guo X, and Yang H (2015) NADC30-like Strain of Porcine Reproductive and Respiratory Syndrome Virus, China. Emerg Infect Dis 21: 2256-2257.