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Abstract

We have designed and built ultrasound imaging-guided HIFU ablative device for preclinical studies on small animals. Before this device is used to treat animals, ex vivo tissue studies were necessary to determine the location and extent of necrotic lesions created inside tissue samples by HIFU beams depending on their acoustic properties. This will allow to plan the beam movement trajectory and the distance and time intervals between exposures leading to necrosis covering the entire treated volume without damaging the surrounding tissues. This is crucial for therapy safety. The objective of this study was to assess the impact of sonication parameters on the size of necrotic lesions formed by HIFU beams generated by 64-mm bowl-shaped transducer used, operating at 1.08 MHz or 3.21 MHz. Multiple necrotic lesions were created in pork loin samples at 12.6-mm depth below tissue surface during 3-s exposure to HIFU beams with fixed duty-cycle and varied pulse-duration or fixed pulse-duration and varied duty-cycle, propagated in two-layer media: water-tissue. After exposures, the necrotic lesions were visualized using magnetic resonance imaging and optical imaging (photos) after sectioning the samples. Quantitative analysis of the obtained results allowed to select the optimal sonication and beam movement parameters to support planning of effective therapy.
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Authors and Affiliations

Łukasz Fura
1
Wojciech Dera
2
Cezary Dziekoński
2
Maciej Świątkiewicz
3
Tamara Kujawska
1

  1. Department of Ultrasound Institute of Fundamental Technological Research, Polish Academy of Sciences
  2. Department of Theory of Continuous Media and Nanostructures Institute of Fundamental Technological Research, Polish Academy of Sciences
  3. Department of Experimental Pharmacology Mossakowski Medical Research Centre, Polish Academy of Sciences
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Abstract

The unpredictable and huge data generation nowadays by smart devices from IoT and mobile Crowd Sensing applications like (Sensors, smartphones, Wi-Fi routers) need processing power and storage. Cloud provides these capabilities to serve organizations and customers, but when using cloud appear some limitations, the most important of these limitations are Resource Allocation and Task Scheduling. The resource allocation process is a mechanism that ensures allocation virtual machine when there are multiple applications that require various resources such as CPU and I/O memory. Whereas scheduling is the process of determining the sequence in which these tasks come and depart the resources in order to maximize efficiency. In this paper we tried to highlight the most relevant difficulties that cloud computing is now facing. We presented a comprehensive review of resource allocation and scheduling techniques to overcome these limitations. Finally, the previous techniques and strategies for allocation and scheduling have been compared in a table with their drawbacks.
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Authors and Affiliations

Abbas M. Ali Al-muqarm
1 2
Naseer Ali Hussien
3

  1. University of Kufa, Iraq
  2. Computer Technical Engineering Department, The Islamic University, Iraq
  3. Alayen University, Iraq
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Abstract

From multi-dialogue to monologue in spoken Italian: the pragmatic/prosodic basis of multi-dialogue and its transformation in narrative and descriptive monologues – The paper summarizes the Language into Act Theory (L-AcT), according to which spoken texts are analysed and aligned per utterance to the acoustic source. Three stretches of spoken Italian taken from the LABLITA Corpus (multi-dialogue, dialogue, monologue) are described according to L-AcT as regards turn-taking, information structure, and illocution. The above texts are then compared to a short literary excerpt showing the different syntactic architecture of the two language varieties.

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Authors and Affiliations

Emanuela Cresti
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Abstract

The private correspondence between Françoise de Graffigny and Antoine-François Devaux allows us to trace the genesis of the epistolary novel Lettres d'une Péruvienne and the five-act play Cénie, two works considered best-sellers of the 18th century. These letters help us understand her working methods (self- censorship, her conception of the female author, her relationship with her main characters, her surrounding environment, etc.) as well as the motivations behind her writing (primarily the need for money), to the extent that they can be considered drafts of both works. The interplay between Françoise de Graffigny’s biography and her fictional female characters is evident from the start, and the reconstruction of the genesis of these works demonstrates how literary creation becomes a means of self- reflection and the creation of a feminine self. This contribution will seek to demonstrate how, in her two most well-known works, Graffigny uses the figure of the stranger, in all its senses, to highlight the difficulties women faced in 18th-century society, showing through the cases of Zilia and Cénie that women were considered ‘like’ foreigners in their own country, in their own homes.
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Authors and Affiliations

Ylenia De Luca
1
ORCID: ORCID

  1. Università degli Studi di Bari

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