The effects of florfenicol on lymphocyte subsets and humoral immune response in mice

Journal title

Polish Journal of Veterinary Sciences




No 2


Divisions of PAS

Nauki Biologiczne i Rolnicze


Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn




DOI: 10.2478/v10181-011-0029-4 ; ISSN 1505-1773


Polish Journal of Veterinary Sciences; 2011; No 2


P Adams (1987), Tissue concentrations and pharmacokinetics of florfenicol in male veal calves given repeated doses, Am J Vet Res, 48, 1725. ; N Afifi (1997), Tissue concentrations and pharmacokinetics of florfenicol in broiler chickens, Brt Poult Sci, 38, 425, ; B Ali (2003), Comparative plasma pharmacokinetics and tolerance of florfenicol following intramuscular and intravenous administration to camels, sheep and goats, Vet Res Commun, 27, 475, ; K Bretzlaff (1987), Florfenicol in non-lactating dairy cows: pharmacokinetics, binding to plasma proteins, and effects on phagocytosis by blood neutrophils, J Vet Phamacol Ther, 10, 233, ; M Cannon (1990), Comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives, J Antimicrobial Chemotherapy, 26, 307, ; J Couderc (1983), Specification of the immune response: its suppression induced by chloramphenicol in vitro, Biosci Rep, 3, 19, ; P Dowling (2006), Antimicrobial Therapy in Veterinary Medicine, 241. ; H El-Banna (1998), Pharmacokinetics of florfenicol in normal and Pasteurella-infected Muscovy ducks, Brt Poult Sci, 39, 492, ; L Hudson (1980), Practical Immunology, 247. ; M Ismail (2009), Comparative pharmacokinetics of florfenicol in the chicken, pigeon and quail, Brt Poult Sci, 50, 144, ; V Lane (2004), Intravenous and subcutaneous pharmacokinetics of florfenicol in sheep, J Vet Pharmacol Ther, 27, 191, ; J Liu (2003), Pharmacokinetics of florfenicol in healthy pigs and in pigs experimentally infected with Actinobacillus pleuropneumoniae, Antimicrob Agents Chemother, 47, 820, ; T Lundèn (1999), Effect of florfenicol on the immune response of rainbow trout (Oncorhynchus mykiss), Vet Immunol Immunopathol, 67, 317, ; Q McKeller (1996), Pharmacokinetics and tolerance of florfenicol in Equidae, Equine Vet J, 28, 209, ; R Mishell (1967), Immunization of dissociated spleen cell cultures from normal mice, J Exp Med, 126, 423, ; M Paape (1990), Effects of florfenicol, chloramphenicol and thiamphenicol on phagocytosis, chemiluminescence and morphology of bovine polymorphonuclear neutrophil leukocytes, J Dairy Sci, 73, 1734, ; B Park (2007), Pharmacokinetics of florfenicol and its major metabolite, florfenicol amine, in rabbits, J Vet Pharmacol Ther, 30, 32, ; B Park (2008), Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in dogs, Res Vet Sci, 84, 85, ; J Shen (2003), Bioavailability and pharmacokinetics of florfenicol in broiler chickens, J Vet Pharmacol Ther, 26, 337, ; S Soback (1995), Florfenikol pharmacokinetics in lactating cows after intravenous, intramuscular and intramammary administration, J Vet Pharmacol Ther, 18, 413, ; M Świtała (2007), Pharmacokinetics of florfenicol, thiamphenicol and chloramphenicol in turkeys, J Vet Pharmacol Ther, 30, 145, ; J Van Snick (1990), Interleukin-6: an overview, Annu Rev Immunol, 8, 253, ; K Varma (1986), Pharmacokinetics of florfenicol in veal calves, J Vet Pharmacol Ther, 9, 412, ; X Zhang (2009), Protective effects of florfenicol on acute lung injury induced by lipopolysaccharide in mice, Int Immunopharmacol, 9, 1525, ; X Zhang (2008), Effects of florfenicol on early cytokine responses and survival in murine endotoxemia, Int Immunopharmacol, 8, 982,