Details
Title
Effects of Hermetia illucens larvae full-fat meal and astaxanthin on the microbiome and histomorphology of the large intestine in pigletsJournal title
Polish Journal of Veterinary SciencesYearbook
2026Volume
Vol. 29Issue
No. 1Authors
Affiliation
Szczepanik, K. : Department of Animal Nutrition and Feed Science, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland ; Kierończyk, B. : Department of Animal Nutrition, Poznań University of Life Sciences, Wołyńska 33, 60-637 Poznań, Poland ; Szymkowiak, P. : Department of Animal Nutrition, Poznań University of Life Sciences, Wołyńska 33, 60-637 Poznań, Poland ; Taciak, M. : Department of Animal Nutrition, Institute of Animal Sciences, Warsaw University of Life Sciences, Ciszewskiego 8, 02-786 Warsaw, Poland ; Barszcz, M. : The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland ; Tuśnio, A. : The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland ; Gawin, K. : The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland ; Dobrowolski, P. : Department of Functional Anatomy and Cytobiology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland ; Świątkiewicz, M. : Department of Animal Nutrition and Feed Science, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, PolandKeywords
astaxanthin ; colon fermentation ; colon histomorphometry ; Hermetia illucens ; intestinal microbiotaDivisions of PAS
Nauki Biologiczne i RolniczeCoverage
17–29Publisher
Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in OlsztynBibliography
- AOAC, Association of Official Analytical Chemists (2009) Official methods of analysis of AOAC International, 18th ed. AOAC International, Gaithersburg, MD.
- Barcenilla A, Pryde SE, Martin JC, Duncan SH, Stewart CS, Henderson C, Flint HJ (2000) Phylogenetic relationships of butyrate-producing bacteria from the human gut. Appl Environ Microbiol 66: 1654-1661.
- Barszcz M, Taciak M, Skomiał J (2011) Dose-response effects of tannic acid and protein on growth performance, caecal fermentation, colon morphology, and β-glucuronidase activity of rats. J Anim Feed Sci 20: 613-625.
- Bass LM, Wershil BK (2015) Anatomy, histology, embryology, and developmental anomalies of the small and large intestine. In: Sleisenger and Fordtran’s Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management.
- Biasato I, Ferrocino I, Colombino E, Gai F, Schiavone A, Cocolin L, Vincenti V, Capucchio MT, Gasco L (2020) Effects of dietary Hermetia illucens meal inclusion on cecal microbiota and small intestinal mucin dynamics and infiltration with immune cells of weaned piglets. J Anim Sci Biotechnol 11: 64.
- Biasato I, Ferrocino I, Grego E, Dabbou S, Gai F, Gasco L, Cocolin L, Capucchio MT, Schiavone A (2019) Gut microbiota and mucin composition in female broiler chickens fed diets including yellow mealworm (Tenebrio molitor L). Animals 9: 213.
- Blachier F, Andriamihaja M, Kong XF (2022) Fate of undigested proteins in the pig large intestine: What impact on the colon epithelium? Anim Nutr 9: 110-118.
- Cerilli LA, Greenson JK (2012) The differential diagnosis of colitis in endoscopic biopsy specimens: a review article. Arch Pathol Lab Med 136: 854-864.
- Choi HD, Youn YK, Shin WG (2011) Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr 66: 363-369.
- Ciaraldi TP, Boeder SC, Mudaliar SR, Giovannetti ER, Henry RR, Pettus JH (2023) Astaxanthin, a natural antioxidant, lowers cholesterol and markers of cardiovascular risk in individuals with prediabetes and dyslipidaemia. Diabetes Obes Metab 25: 1985-1994.
- Davila AM, Blachier F, Gotteland M, Andriamihaja M, Benetti PH, Sanz Y, Tomé D (2013) Intestinal luminal nitrogen metabolism: role of the gut microbiota and consequences for the host. Pharmacol Res 69: 1-15.
- Desantis S, Mastrodonato M, Accogli G, Rossi G, Crovace AM (2019) Effects of a probiotic on the morphology and mucin composition of pig intestine. Histol Histopathol 34: 1037-1050.
- Di Lorenzo F, De Castro C, Silipo A, Molinaro A (2019) Lipopolysaccharide structures of Gram-negative populations in the gut microbiota and effects on host interactions. FEMS Microbiol Rev 43: 257-272.
- Duncan SH, Louis P, Thomson JM, Flint HJ (2009) The role of pH in determining the species composition of the human colonic microbiota. Environ Microbiol 11: 2112-2122.
- Eroglu A, Al’Abri IS, Kopec RE, Crook N, Bohn T (2023) Carotenoids and their health benefits as derived via their interactions with gut microbiota. Adv Nutr 14: 238-255.
- Grela ER, Skomiał J (2020) Nutritional recommendations and nutritional value of feed for pigs. The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, Poland.
- Hou G, Peng W, Wei L, Li R, Yuan Y, Huang X, Yin Y (2020) Lactobacillus delbrueckii interfere with bile acid enterohepatic circulation to regulate cholesterol metabolism of growing – finishing pigs via its bile salt hydrolase activity. Front Nutr 7: 617676.
- Huang XZ, Park JT, Kim HG, Lee CK, Won YJ, Park BG, Jeong SW (2011) Phenotype-specific down-regulation of nicotinic acetylcholine receptors in the pelvic ganglia of castrated rats: implications for neurogenic erectile dysfunction. Neurosci Lett 501: 55-59.
- Józefiak D, Józefiak A, Kierończyk B, Rawski M, Świątkiewicz S, Długosz J, Engberg RM (2016) Insects – a natural nutrient source for poultry – a review. Ann Anim Sci 16: 297-313.
- Józefiak D, Kierończyk B, Juśkiewicz J, Zduńczyk Z, Rawski M, Długosz J, Sip A, Højberg O (2013) Dietary nisin modulates the gastrointestinal microbial ecology and enhances growth performance of broiler chickens. PLoS One 8: e85347.
- Kierończyk B, Rawski M, Mikołajczak Z, Homska N, Jankowski J, Ognik K, Józefiak A, Mazurkiewicz J, Józefiak D (2022) Available for millions of years but discovered through the last decade: Insects as a source of nutrients and energy in animal diets. Anim Nutr 11: 60-79.
- Kim SH, Kim H (2019) Astaxanthin modulation of signaling pathways that regulate autophagy. Mar Drugs 17: 546.
- Liu S, Wang J, Li L, Duan Y, Zhang X, Wang T, Zang J, Piao X, Ma Y, Li D (2023) Endogenous chitinase might lead to differences in growth performance and intestinal health of piglets fed different levels of black soldier fly larvae meal. Anim Nutr 14: 411-424.
- MacEdo RC, Bolin AP, Marin DP, Otton R (2010) Astaxanthin addition improves human neutrophils function: In vitro study. Eur J Nutr 49: 447-457.
- Macfarlane GT, Gibson GR, Cummings JH (1992) Comparison of fermentation reactions in different regions of the human colon. J Appl Microbiol 72: 57-64.
- Maltecca C, Bergamaschi M, Tiezzi F (2020) The interaction between microbiome and pig efficiency: A review. J Anim Breed Genet 137: 4-13.
- Martínez I, Muller CE, Walter J (2013) Long-term temporal analysis of the human fecal microbiota revealed a stable core of dominant bacterial species. PLoS One 8: e69621.
- Merchant HA, McConnell EL, Liu F, Ramaswamy C, Kulkarni RP, Basit AW, Murdan S (2011) Assessment of gastrointestinal pH, fluid and lymphoid tissue in the guinea pig, rabbit and pig, and implications for their use in drug development. Eur J Pharm Sci 42: 3-10.
- Nagayama T, Sugimoto M, Ikeda S, Kume S (2014) Effects of astaxanthin-enriched yeast on mucosal IgA induction in the jejunum and ileum of weanling mice. Anim Sci J 85: 449-453.
- Newton GL, Booram CV, Barker RW, Hale OM (1977) Dried Hermetia illucens larvae meal as a supplement for swine. J Anim Sci 44: 395-400.
- Nowak A, Libudzisz Z (2006) Influence of phenol, p-cresol and indole on growth and survival of intestinal lactic acid bacteria. Anaerobe 12: 80-84.
- Pajarillo EAB, Chae JP, Balolong MP, Kim HB, Kang DK (2014) Assessment of fecal bacterial diversity among healthy piglets during the weaning transition. J Gen Appl Microbiol 60: 140-146.
- Pieper R, Boudry C, Bindelle J, Vahjen W, Zentek J (2014) Interaction between dietary protein content and the source of carbohydrates along the gastrointestinal tract of weaned piglets. Arch Anim Nutr 68: 263-280.
- Posthaus H, Kittl S, Tarek B, Bruggisser J (2020) Clostridium perfringens type C necrotic enteritis in pigs: diagnosis, pathogenesis, and prevention. J Vet Diagn Invest 32: 203-212.
- Rist VTS, Weiss E, Eklund M, Mosenthin R (2013) Impact of dietary protein on microbiota composition and activity in the gastrointestinal tract of piglets in relation to gut health: A review. Animal 7: 1067-1078.
- Russell EG (1979) Types and distribution of anaerobic bacteria in the large intestine of pigs. Appl Environ Microbiol 37: 187-193.
- Shah SRA, Çetingül IS (2022) Nutritive value of black soldier fly (Hermetia illucens) as economical and alternative feedstuff for poultry diet. J Worlds Poult Res 12: 1-7.
- Szczepanik K, Furgał-Dierżuk I, Gala Ł, Świątkiewicz M (2023) Effects of Hermetia illucens larvae meal and astaxanthin as feed additives on health and production indices in weaned pigs. Animals 13: 163.
- Szczepanik K, Świątkiewicz M (2024) Hermetia illucens as a source of antimicrobial peptides – a review of in vitro and in vivo studies. Ann Anim Sci 24: 77-88.
- Taciak M, Barszcz M, Święch E, Tuśnio A, Bachanek I (2017) Interactive effects of protein and carbohydrates on production of microbial metabolites in the large intestine of growing pigs. Arch Anim Nutr 71: 192-209.
- Taciak M, Barszcz M, Tuśnio A, Pastuszewska B (2015) Interactive effects of indigestible carbohydrates, protein type, and protein level on biomarkers of large intestine health in rats. PLoS One 10: e0142176.
- Tang Q, Xu E, Wang Z, Xiao M, Cao S, Hu S, Wu Q, Xiong Y, Jiang Z, Wang F, Yang G, Wang L, Yi H (2022) Dietary Hermetia illucens larvae meal improves growth performance and intestinal barrier function of weaned pigs under the environment of enterotoxigenic Escherichia coli K88. Front Nutr 8: 812011.
- Tang X, Xiong K, Fang R, Li M (2022) Weaning stress and intestinal health of piglets: A review. Front Immunol 13: 1042778.
- Triunfo M, Tafi E, Guarnieri A, Salvia R, Scieuzo C, Hahn T, Zibek S, Gagliardini A, Panariello L, Coltelli MB, De Bonis A, Falabella P (2022) Characterization of chitin and chitosan derived from Hermetia illucens, a further step in a circular economy process. Sci Rep 12: 6613.
- Uchiyama A (2008) Clinical efficacy of astaxanthin-containing Haematococcus pluvialis extract for volunteers at risk of metabolic syndrome. J Clin Biochem Nutr 43: 38-43.
- Walker AW, Duncan SH, McWilliam Leitch EC, Child MW, Flint HJ (2005) pH and peptide supply can radically alter bacterial populations and short-chain fatty acid ratios within microbial communities from the human colon. Appl Environ Microbiol 71: 3692-3700.
- Wang M, Ma H, Guan S, Luo T, Zhao C, Cai G, Zheng Y, Jia X, Di J, Li R, Cui H (2021) Astaxanthin from Haematococcus pluvialis alleviates obesity by modulating lipid metabolism and gut microbiota in mice fed a high-fat diet. Food Funct 12: 9719-9738.
- Wu L, Lyu Y, Srinivasagan R, Wu J, Ojo B, Tang M, El-Rassi GD, Metzinger K, Smith BJ, Lucas EA, Clarke SL, Chowanadisai W, Shen X, He H, Conway T, von Lintig J, Lin D (2020) Astaxanthin-shifted gut microbiota is associated with inflammation and metabolic homeostasis in mice. J Nutr 150: 2687-2698.
- Xu Y, Wang Z, Wang Y, Yan S, Shi B (2018) Effects of chitosan as growth promoter on diarrhea, nutrient apparent digestibility, fecal microbiota and immune response in weaned piglets. J Appl Anim Res 46: 1437-1442.
- Yang Y, Seo JM, Nguyen A, Pham TX, Park HJ, Park Y, Kim B, Bruno RS, Lee J (2011) Astaxanthin-rich extract from the green alga Haematococcus pluvialis lowers plasma lipid concentrations and enhances antioxidant defense in apolipoprotein E knockout mice. J Nutr 141: 1611-1617.
- Yu M, Li Z, Chen W, Rong T, Wang G, Ma X (2019) Hermetia illucens larvae as a potential dietary protein source altered the microbiota and modulated mucosal immune status in the colon of finishing pigs. J Anim Sci Biotechnol 10: 1-16.
- Zhu LH, Zhao KL, Chen XL, Xu JX (2012) Impact of weaning and an antioxidant blend on intestinal barrier function and antioxidant status in pigs. J Anim Sci 90: 2581-2589.
- Zhu X, Hao R, Zhang J, Tian C, Hong Y, Zhu C, Li G (2022) Dietary astaxanthin improves the antioxidant capacity, immunity and disease resistance of coral trout (Plectropomus leopardus). Fish Shellfish Immunol 122: 38-47.