TitleImpact of bioreactor scale on lovastatin biosynthesis by Aspergillus terreus ATCC 20542 in a batch culture
Journal titleChemical and Process Engineering
IssueNo 1 March
Keywordslovastatin ; Aspergillus terreus ATCC 20542 ; shake flask ; stirred tank bioreactor ; batch process
Divisions of PASNauki Techniczne
PublisherPolish Academy of Sciences Committee of Chemical and Process Engineering
TypeArtykuły / Articles
IdentifierDOI: 10.2478/v10176-012-0007-0 ; ISSN 0208-6425
SourceChemical and Process Engineering; 2012; No 1 March; 71-84
ReferencesBizukojć M. (2007a), A macrokinetic modelling of the biosynthesis of lovastatin by, Aspergillus terreus. J. Biotechnol, 130, 422, doi.org/10.1016/j.biotec.2007.05.007 ; Bizukojć M. (2007b), Simultaneous biosynthesis of (+)-geodin by a lovastatin-producing fungus, Aspergillus terreus. J. Biotechnol, 132, 453, doi.org/10.1016/j.jbiotec.2006.06.017 ; Bizukojć M. (2008), Biosynthesis of lovastatin and (+)-geodin by <i>Aspergillus terreus</i> in batch and fed-batch culture in the stirred tank bioreactor, Biochem. Eng, 42, 198, doi.org/10.1016/j.bej.2008.06.022 ; Bizukojć M. (2011), Lovastatin and (+)-geodin formation by <i>Aspergillus terreus</i> ATCC 20542 in a batch culture with the simultaneous use of lactose and glycerol as carbon sources, Eng. Life Sci, 11, 272, doi.org/10.1002/elsc.201000179 ; J. Casas Lopez (2003), Production of lovastatin by <i>Aspergillus terreus:</i> effects of C:N ratio and the principal nutrients on growth and metabolite production, Enzyme Microb. Technol, 33, 270, doi.org/10.1016/S0141-0229(03)00130-3 ; J. Casas Lopez (2004), Fermentation optimization for the production of lovastatin by <i>Aspergillus terreus</i>; use of response surface methodology, J. Chem. Technol. Biotechnol, 79, 1119, doi.org/10.1002/jctb.1100 ; J. Casas Lopez (2005), Pellet morphology, culture rheology and lovastatin production in cultures of, Aspergillus terreus. J. Biotechnol, 116, 61, doi.org/10.1016/j.jbiotec.2004.10.005 ; Hajjaj H. (2001), Lovastatin biosynthesis by <i>Aspergillus terreus</i> in a chemically defined medium, Appl. Environ. Microbiol, 67, 2596, doi.org/10.1128/AEM.67.6.2596-2602.2001 ; Kennedy J. (1999), Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis, Science, 284, 1368, doi.org/10.1126/science.284.5418.1368 ; Kumar M. (2000), Repeated fed-batch process for improving lovastatin production, Proc. Biochem, 36, 363, doi.org/10.1016/S0032-9592(00)00222-3 ; Lai L-S. (2002), Medium optimization for lovastatin production by Aspergillus terreus in submerged cultures, J. Chin. Inst. Chem. Engrs, 33, 517. ; L-S Lai (2005), The influence of culturing environments on lovastatin production by <i>Aspergillus terreus</i> in submerged cultures, Enz. Microb. Technol, 36, 737, doi.org/10.1016/j.enzmictec.2004.12.021 ; Manzoni M. (1998), Production of statinsby filamenous fungi, Biotechnol. Lett, 21, 253, doi.org/10.1023/A:1005495714248 ; E. Rodriguez Porcel (2006), <i>Aspergillus terreus</i> broth rheology, oxygen transfer, and lovastatin production in a gas-agitated slurry reactor, Ind. Eng. Chem. Res, 45, 4837, doi.org/10.1021/ie0600801
Ali Mesbach, UC Berkeley, USA
Anna Gancarczyk, Institute of Chemical Engineering, Polish Academy of Sciences, Poland
Anna Trusek, Wrocław University of Science and Technology, Poland
Bettina Muster-Slawitsch, AAE Intec, Austria
Daria Camilla Boffito, Polytechnique Montreal, Canada
Donata Konopacka-Łyskawa, Gdańsk University of Technology, Poland
Dorota Antos, Rzeszów University of Technology, Poland
Evgeny Rebrov, University of Warwick, UK
Georgios Stefanidis, National Technical University of Athens, Greece
Ireneusz Grubecki, Bydgoszcz Univeristy of Science and Technology, Poland
Johan Tinge, Fibrant B.V., The Netherlands
Katarzyna Bizon, Cracow University of Technology, Poland
Katarzyna Szymańska, Silesian University of Technology, Poland
Marcin Bizukojć, Łódź University of Technology, Poland
Marek Ochowiak, Poznań University of Technology, Poland
Mirko Skiborowski, Hamburg University of Technology, Germany
Nikola Nikacevic, University of Belgrade, Serbia
Rafał Rakoczy, West Pomeranian University of Technology, Poland
Richard Lakerveld, Hong Kong University of Science and Technology, Hong Kong
Tom van Gerven, KU Leuven, Belgium
Tomasz Sosnowski, Warsaw University of Technology, Poland
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