The article discusses the architectural expression of houses built on water, based on the design process of the floating house in the Czerniakowski Port in Warsaw, designed by Mai Bui Ngoc and Rafał Mazur. The question of the form of the floating house was the starting point of the work on this project. Usually buildings are designed in a specific location, which gives architects an inspiration for the design of the new form. In the case of the floating houses the goal was to make a universal artefact as a car or a phone. This artefact should be more connected to the owner than to the landscape. This artefact should be also neutral to the landscape and it should not be destructive for the surroundings. The answer lays between two archetypes; a typical house and a boat. Analysis of the existing floating houses gave the conclusion that authors of these houses were usually very close to one of these two archetypes. It is a need to put a lot of effort to design an object which does not remind a real house and a yacht design.
The aim of this study was to evaluate the intestinal and cardiac biomarkers in the determination of intestinal and cardiac damage in dogs with parvoviral enteritis. The material of this study consisted of 10 healthy dogs (control group) and 30 dogs with parvoviral enteritis (experimental group) admitted to the Department of Internal Medicine, Faculty of Veterinary Medicine, Selcuk University.
Serum samples were extracted from the collected blood samples taken from vena cephalica venipuncture for analysis of blood gases, haemogram and to measure the levels of intestinal-fatty acid-binding protein (I-FABP), trefoil factor 3 (TFF-3), claudin-3 (CLDN-3), heart-type fatty acid-binding protein (H-FABP), cardiac troponin I (cTnI), and creatine kinase-myocardial band (CK-MB) by enzyme linked immunosorbent assay (ELISA) test kits.
Statistically significant decreases in the blood gas hydrogen ion concentration (pH), partial pressure of oxygen (pO2), sodium (Na), bicarbonate (HCO3), and oxygen saturation (SatO2) levels and significant increase in the levels of I-FABP, TFF-3, CK-MB, cTnI and also in the haemogram, a decrease in leukocyte (WBC) level and an increase in platelet (THR) level were detected in parvoviral dogs compared to the control group (p<0.05). Also ROC analysis revealed on 0th hour for the utility of I-FABP and on 48th hour for TFF-3 in differentiating in the experimental group between the survivor and non-survivor dogs. Other intestinal-related biomarker (CLDN-3) and none of the cardiac-related biomarkers (H-FABP, CK-MB and cTnI) are not high enough for prediction of mortality.
In conclusion, it was determined that I-FABP and TFF-3 for the intestinal injury and mortality prediction, and CK-MB and cTnI for the cardiac injury were useful and reliable biomarkers to determine the damage caused by parvovirus in dogs.
Matrix metalloproteinases 2 and 9 (MMP2 and MMP9) are proteolytic enzymes involved with extracellular matrix degradation. They play a role in tumor invasion and metastases. Be- cause of their ability to degrade signaling molecules presented in extracellular matrix, MMPs contribute to tumor proliferation and apoptosis. The aim of this study was to evaluate expression of MMP2 (latent and both active and latent forms) and MMP9 (active, latent, active and latent forms) in different subtypes of canine lymphomas and their relationship with proliferative (mi- totic index and percentage of Ki67-positive cells) and apoptotic (apoptotic index) markers. Ex- pression of MMPs was assessed immunohistochemically using an immunoreactive score system. Expression of both MMPs was found in all 20 examined lymphomas belonging to six subtypes. Most cases showed a moderate level of all analyzed forms of MMP2 and MMP9. High expres- sion of MMPs was found in single cases. Except for a positive correlation between the active form of MMP9 and the mitotic index for all lymphoma cases, no other correlations between any remaining forms of MMPs and neither proliferative nor apoptotic markers were found, irrespec- tive of whether the analysis encompassed all cases or the most numerous lymphoma subtypes i.e. centroblastic and Burkitt-like. Our results were not able to clearly confirm the influence of MMPs on the proliferation and apoptotic activity of canine lymphoma cells. However, further studies examining MMPs activity by zymography, expression of their inhibitors and other factors in- volved in activation of cell proliferation and apoptosis inhibition are needed to clarify the role of MMPs, especially the active form of MMP9, in the behavior of canine lymphoma cells.
The aim of the presented paper was to verify the impact of Dynamic PUCCH Resource Allocation Algorithm of the LTE cellular system on the maximum uplink cell throughput and call setup success rate-CSSR. Paper includes the laboratorytestbeddescription and presents the results of an experiment confirming the improvement of both key performance indicatorsKPIs.Apart from the presentation of the Dynamic PUCCH Resource allocation algorithm, the paper also includes a description of legacy LTE uplink (PUCCH and PUSCH) channels dimensioning process thus filling the gap of such a tutorial in the available literature.
The article presents a constitutive model for Shape Memory Alloys (SMA) along with result of dynamic simulations of SMA model. The applications of devices incorporating SMA in civil engineering focus mostly on mitigation of the seismic hazard effects in new-build and historical buildings or improvement of fatigue resilience. The unique properties of SMA, such as shape memory effect and superelasticity give promising results for such applications. The presented model includes additional phenomenon of SMA – internal loops. The paper shows the method of formulation of physical relations of SMA based on special rheological structure, which includes modified Kepes’s model. This rheological element, introduced as dual-phase plasticity body, is given in the context of martensite phase transformation. One of the advantages of such an approach is a possibility of formulation of constitutive relationships as a set of explicit differential equations. The application of the model is demonstrated on example of dynamic simulations of three dimensional finite element subjected to dynamic excitation.
The influence of rebar, protruding from concrete element during casting, on temperature and strength development was analyzed. Test models of size 50 cm x 50 cm x 50 cm were made with and without protruding rebar. The rebar protruding from the sample simulated the conditions of the hardening of elements such as bridge abutments or pylons, which require technological break. Samples were cast in insulated formworks, to create semi-adiabatic conditions for concrete curing, simulating real conditions of curing of mass structures. The research utilized selfconsolidating concrete with two different rapid hardening cements: CEM I 42.5R and CEM I 52.5R, and blastfurnace cement CEM III/A 42.5N. Continuous registration of temperatures in the samples was performed for the first 7 days. Based on the results acquired and compressive strength, the amount and kinetics of the heat given off in the concrete was determined and an evaluation of its strength in conditions simulating actual conditions was performed. The research showed that the difference in temperature between the reinforced and non-reinforced sample was approximately 14.0° C.