Growth factor and cytokine interactions in myogenesis. Part I. The effect of TNF-α and IFN-γ on IGF-I-dependent differentiation in mouse C2C12 myogenic cells

Journal title

Polish Journal of Veterinary Sciences




No 3


Divisions of PAS

Nauki Biologiczne i Rolnicze


Polish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn




DOI: 10.2478/v10181-011-0062-3 ; ISSN 1505-1773


Polish Journal of Veterinary Sciences; 2011; No 3


L Abad (2002), Cytokine responses differ by compartment and wasting status in patients with HIV infection and healthy controls, Cytokine, 18, 286, ; Y Cao (2006), Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters, EMBO J, 25, 502, ; S Chen (2007), TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK, Am J Physiol Cell Physiol, 292. ; M Cheng (2008), Endogenous interferon-g is required for efficient skeletal muscle regeneration, Am J Physiol Cell Physiol, 294. ; R Cheng (2007), Cyclin A2 induces cardiac regeneration after myocardial infarction and prevents heart failure, Circ Res, 100, 1741, ; S Dedieu (2002), Involvement of myogenic regulator factors during fusion in the cell line C2C12, Int J Dev Biol, 46, 235. ; M Dehoux (2007), IGF-I does not prevent myotube atrophy caused by proinflammatory cytokines despite activation of Akt/Foxo and GSK-3beta pathways and inhibition of atrogin-1 mRNA, Am J Physiol Endocrinol Metab, 292. ; S Di Marco (2005), NF-kappa B-mediated MyoD decay during muscle wasting requires nitric oxide synthase mRNA stabilization, HuR protein, and nitric oxide release, Mol Cell Biol, 25, 6533, ; S Goetsch (2003), Transcriptional profiling and regulation of the extracellular matrix during muscle regeneration, Physiol Genomics, 14, 261. ; K Grzelkowska-Kowalczyk (2010), Treatment with TNF-α and IFN-γ alters the activation of Ser/Thr protein kinases and the metabolic response to IGF-I in mouse C2C12 myogenic cells, Cell Mol Biol Lett, 15, 13, ; K Grzelkowska-Kowalczyk (2006), Exposure to TNF-α but not IL-1β impairs insulin-dependent phosphorylation of protein kinase B and p70S6k in mouse C2C12 myogenic cells, Pol J Vet Sci, 9, 1. ; M Ishido (2004), In vivo expression patterns of MyoD, p21, and Rb proteins in myonuclei and satellite cells of denervated rat skeletal muscle, Am J Physiol Cell Physiol, 287. ; M Karalaki (2009), Muscle regeneration: cellular and molecular events, In Vivo, 23, 779. ; M Kitzmann (1998), The muscle regulatory factors MyoD and Myf-5 undergo distinc cell cycle-specific expression in muscle cells, J Cell Biol, 142, 1447, ; R Langen (2004), Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization, FASEB J, 18, 227, ; Y Li (2001), TNF-alpha regulates early differentiation of C2C12 myoblasts in an autocrine fashion, FASEB J, 15, 1413. ; S Madihally (2002), Interferon gamma modulates trauma-induced muscle wasting and immune dysfunction, Ann Surg, 236, 649, ; J O'Connor (2008), Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology, Cell Immunol, 252, 91, ; A Paul (2002), Different modes of hypertrophy in skeletal muscle fibers, J Cell Biol, 156, 751, ; A Saini (2006), Waste management - cytokines, growth factors and cachexia, Cytokine Growth Factor Rev, 17, 475, ; A Saini (2008), Proand anti-apoptotic roles for IGF-I in TNF-α-induced apoptosis: a MAP kinase mediated mechanism, Growth Factors, 26, 239, ; M Tisdale (2008), Catabolic mediators of cancer cachexia, Curr Opin Support Palliat Care, 2, 256, ; L Tintignac (2005), Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase, J Biol Chem, 280, 2847, ; S Yeh (2008), The cytokine basis of cachexia and its treatment: are they ready for prime time?, J Am Med Dir Assoc, 9, 219,